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Anti-ASGR2 Antibody-PE (3P650) is a PE-conjugated Rabbit antibody targeting ASGR2. Anti-ASGR2 Antibody-PE (3P650) can be used in FCM.
Description | Anti-ASGR2 Antibody-PE (3P650) is a PE-conjugated Rabbit antibody targeting ASGR2. Anti-ASGR2 Antibody-PE (3P650) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 3P650 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human ASGR2 expression on HepG2 cells. Cells were stained with PE-conjugated anti-Human ASGR2. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ASGR2 / ASGPR2 (rh ASGR2 / ASGPR2; TMPY-02909; P07307-1; Gln80-Ala311) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
Research Background | ASGR2 is a subunit of the asialoglycoprotein receptor. Asialoglycoprotein receptor, also known as the Ashwell receptor, which is specific for desialylated (galactosyl-terminal) glycoproteins and is expressed exclusively in hepatic parenchymal cells. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. ASGR2 is a glycoprotein. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. ASGR2 is the less abundant minor subunit. |
Conjucates | PE |
Others Formats | Unconjugated |
Antibody Types Available | 2 |
Immunogen | Recombinant Human ASGR2 / ASGPR2 Protein (TMPY-02909) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
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