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Anti-Osteoactivin/GPNMB Antibody (7E107)
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Catalog No. TMAY-01838
Alias Osteoactivin, NMB, HGFIN, glycoprotein (transmembrane) nmb
Anti-Osteoactivin/GPNMB Antibody (7E107) is a Rabbit antibody targeting Osteoactivin/GPNMB. Anti-Osteoactivin/GPNMB Antibody (7E107) can be used in ELISA.
Anti-Osteoactivin/GPNMB Antibody (7E107)
Anti-Osteoactivin/GPNMB Antibody (7E107)
😃Good
Catalog No. TMAY-01838Alias Osteoactivin, NMB, HGFIN, glycoprotein (transmembrane) nmb
Anti-Osteoactivin/GPNMB Antibody (7E107) is a Rabbit antibody targeting Osteoactivin/GPNMB. Anti-Osteoactivin/GPNMB Antibody (7E107) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | Osteoactivin, NMB, HGFIN, glycoprotein (transmembrane) nmb |
| Ig Type | Rabbit IgG |
| Clone | 7E107 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human GPNMB / Osteoactivin (rh GPNMB / Osteoactivin; TMPY-02143; Q14956-2; Met1-Pro474). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | GPNMB belongs to the PMEL / NMB family, also known as Osteoactivin and Hematopoietic growth factor-inducible neurokinin 1 ( HGFIN ), is a transmembrane glycoprotein that is expressed in numerous cells, including osteoclasts, macrophages, dendritic cells, and tumor cells. It is suggested to influence osteoblast maturation, cell adhesion, and migration. GPNMB protein acts as a downstream mediator of BMP-2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization and functions as a negative regulator of inflammation in macrophages. Osteoactivin is expressed at high levels in normal and inflammatory liver macrophages suggesting a significant role in acute liver injury. The early-phase upregulation of Osteoactivin expression in the tubular epithelium in response to renal injury might play a role in triggering renal interstitial fibrosis via activation of matrix metalloproteinase expression and collagen remodeling in rats. Osteoactivin is a protein that is expressed in aggressive human breast cancers and is capable of promoting breast cancer metastasis to bone. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human GPNMB / Osteoactivin Protein (TMPY-02143) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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