Anti-NLRP3 Polyclonal Antibody 3

Name: Anti-NLRP3 Polyclonal Antibody 3
Brand: TargetMol
SKU: TMAB-01245
Rating: 4.5 (1 reviews)

(Synonyms: PYRIN-containing APAF1-like protein 1, Pypaf1, Nlrp3, Nalp3, NACHT, LRR and PYD domains-containing protein 3, Mmig1, Mast cell maturation-associated-inducible protein 1, LRR and PYD domains-containing protein 3, Cryopyrin, Cold autoinflammatory syndrome 1 protein homolog, Cias1) Copy Product Info

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Synonyms: PYRIN-containing APAF1-like protein 1, Pypaf1, Nlrp3, Nalp3, NACHT, LRR and PYD domains-containing protein 3, Mmig1, Mast cell maturation-associated-inducible protein 1, LRR and PYD domains-containing protein 3, Cryopyrin, Cold autoinflammatory syndrome 1 protein homolog, Cias1

Catalog No. TMAB-01245 Copy Product Info

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Anti-NLRP3 Polyclonal Antibody 3 is a Rabbit antibody targeting NLRP3. Anti-NLRP3 Polyclonal Antibody 3 can be used in WB.

Anti-NLRP3 Polyclonal Antibody 3

Pack Size	Price	USA Stock	Global Stock
50 μL	$221	7-10 days	7-10 days
100 μL	$372	7-10 days	7-10 days
200 μL	$527	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:/

Appearance:Liquid

Color:Transparent

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COA Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-NLRP3 Polyclonal Antibody 3 is a Rabbit antibody targeting NLRP3. Anti-NLRP3 Polyclonal Antibody 3 can be used in WB.
Synonyms	PYRIN-containing APAF1-like protein 1, Pypaf1, Nlrp3, Nalp3, NACHT, LRR and PYD domains-containing protein 3, Mmig1, Mast cell maturation-associated-inducible protein 1, LRR and PYD domains-containing protein 3, Cryopyrin, Cold autoinflammatory syndrome 1 protein homolog, Cias1
Ig Type	IgG
Reactivity	Human,Mouse (predicted:Rat)

Application	WB
Recommended Dose	WB: 1:500-2000
Antibody Type	Polyclonal
Host Species	Rabbit
Subcellular Localization	Cytoplasm.
Tissue Specificity	Expressed in blood leukocytes. Strongly expressed in polymorphonuclear cells and osteoblasts. Undetectable or expressed at a lower magnitude in B- and T-lymphoblasts, respectively. High level of expression detected in chondrocytes. Detected in non-keratin
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1 mg/mL
Research Background	May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. Subcellular Location : Cytoplasm.

Antigen Details

Immunogen	KLH conjugated synthetic peptide: mouse NALP3/CIAS1
Antigen Species	Mouse
Gene Name	NLRP3
Gene ID	216799
Protein Name	NACHT, LRR and PYD domains-containing protein 3
Uniprot ID	Q8R4B8
Biology Area	TNF,Inflammatory mediators,Macrophage / Inflamm.,NFkB Pathway
Function	May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.