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Anti-NLRP3 Polyclonal Antibody 3

😃Good
Catalog No. TMAB-01245

Anti-NLRP3 Polyclonal Antibody 3 is a Rabbit antibody targeting NLRP3. Anti-NLRP3 Polyclonal Antibody 3 can be used in WB.

Anti-NLRP3 Polyclonal Antibody 3

Anti-NLRP3 Polyclonal Antibody 3

😃Good
Catalog No. TMAB-01245
Anti-NLRP3 Polyclonal Antibody 3 is a Rabbit antibody targeting NLRP3. Anti-NLRP3 Polyclonal Antibody 3 can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$221 7-10 days
100 μL$372 7-10 days
200 μL$527 7-10 days
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Instruction Manual of Detection Antibody
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Product Introduction

Bioactivity
Description
Antibody Type: Rabbit Polyclonal

Application: WB

Reactivity: Mouse,Rat (predicted:Human)
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human)
Verified Activity
Sample:
Lane 1: LympHnode (Mouse) Lysate at 40 μg
Lane 2: Lung (Mouse) Lysate at 40 μg
Lane 3: Spleen (Mouse) Lysate at 40 μg
Lane 4: Lung (Rat) Lysate at 40 μg
Lane 5: Spleen (Rat) Lysate at 40 μg
Primary: Anti-NALP3/CIAS1 (TMAB-01245) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 114-118 kDa
Observed band size: 120 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundMay function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. Subcellular Location : Cytoplasm.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse NALP3/CIAS1
Antigen Species
Mouse
Gene ID
216799
Uniprot ID
Biology Area
TNF,Inflammatory mediators,Macrophage / Inflamm.,NFkB Pathway
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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