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PROTAC FAK degrader 1

Name: PROTAC FAK degrader 1
Brand: TargetMol
SKU: T13840
Rating: 4.5 (1 reviews)

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Catalog No. T13840Cas No. 2301916-69-6

PROTAC FAK degrader 1 is a selective and potent degrader of focal adhesion kinase (Fak) with an IC50 of 6.5 nM.

PROTAC FAK degrader 1

😃Good

Catalog No. T13840Cas No. 2301916-69-6

PROTAC FAK degrader 1 is a selective and potent degrader of focal adhesion kinase (Fak) with an IC50 of 6.5 nM.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$456	Backorder	Backorder
5 mg	$813	Backorder	Backorder
10 mg	$1,240	Backorder	Backorder
50 mg	Inquiry	Backorder	Backorder
100 mg	Inquiry	Backorder	Backorder

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	PROTAC FAK degrader 1 is a selective and potent degrader of focal adhesion kinase (Fak) with an IC50 of 6.5 nM.
Targets&IC50	FAK:3 nM (DC50), FAK:6.5 nM

Chemical Properties

Molecular Weight	996.13
Formula	C₄₇H₅₆F₃N₉O₈S₂
Cas No.	2301916-69-6
Relative Density.	1.368 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 200 mg/mL (200.78 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.0039 mL	5.0194 mL	10.0389 mL	50.1943 mL
5 mM	0.2008 mL	1.0039 mL	2.0078 mL	10.0389 mL
10 mM	0.1004 mL	0.5019 mL	1.0039 mL	5.0194 mL
20 mM	0.0502 mL	0.2510 mL	0.5019 mL	2.5097 mL
50 mM	0.0201 mL	0.1004 mL	0.2008 mL	1.0039 mL
100 mM	0.0100 mL	0.0502 mL	0.1004 mL	0.5019 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc