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(-)-Oxypeucedanin hydrate

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Catalog No. T5808Cas No. 133164-11-1
Alias OXYPEUCEDANIN HYDRATE

(-)-Oxypeucedanin hydrate is a furanocoumarin. It has a role as a metabolite.

(-)-Oxypeucedanin hydrate
Other Forms of (-)-Oxypeucedanin hydrate:

(-)-Oxypeucedanin hydrate

🥰Excellent
Catalog No. T5808Alias OXYPEUCEDANIN HYDRATECas No. 133164-11-1
(-)-Oxypeucedanin hydrate is a furanocoumarin. It has a role as a metabolite.
Pack SizePriceAvailabilityQuantity
1 mg$98In Stock
5 mg$247In Stock
10 mg$372In Stock
25 mg$613In Stock
1 mL x 10 mM (in DMSO)$255In Stock
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Purity:≥95%
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COA HNMR

Product Introduction

Bioactivity
Description
(-)-Oxypeucedanin hydrate is a furanocoumarin. It has a role as a metabolite.
In vitro
Oxypeucedanin exhibited marginal toxicity on normal fibroblast cells and sensitive parental mouse lymphoma cells;?furthermore, they were less toxic on multidrug resistant lymphoma cells.? Oxypeucedanin showed moderate MDR reversing activity.?In the checkerboard assay, oxypeucedanin and heraclenin showed slight synergistic effect with doxorubicin.?These compounds might improve the cytotoxic effect of the standard chemotherapeutic drug doxorubicin.
Cell Research
Pure compounds were isolated from the extract of aerial parts of the plant by chromatographic methods.Bioactivities were tested on multidrug resistant and sensitive mouse T-lymphoma cell lines.The inhibition of the cancer MDR efflux pump ABCB1 was evaluated by flow cytometry (at 2 and 20 μM).A checkerboard microplate method was applied to study the interactions of furocoumarins and doxorubicin.Toxicity was studied using normal murine NIH/3T3 fibroblasts.
SynonymsOXYPEUCEDANIN HYDRATE
Chemical Properties
Molecular Weight304.29
FormulaC16H16O6
Cas No.133164-11-1
SmilesCC(C)(O)[C@@H](O)COc1c2ccoc2cc2oc(=O)ccc12
Relative Density.1.386 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (180.75 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2863 mL16.4317 mL32.8634 mL164.3169 mL
5 mM0.6573 mL3.2863 mL6.5727 mL32.8634 mL
10 mM0.3286 mL1.6432 mL3.2863 mL16.4317 mL
20 mM0.1643 mL0.8216 mL1.6432 mL8.2158 mL
50 mM0.0657 mL0.3286 mL0.6573 mL3.2863 mL
100 mM0.0329 mL0.1643 mL0.3286 mL1.6432 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

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