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(-)-Oxypeucedanin hydrate

Name: (-)-Oxypeucedanin hydrate
Brand: TargetMol
SKU: T5808
Price: 98 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5808Cas No. 133164-11-1

Alias OXYPEUCEDANIN HYDRATE

(-)-Oxypeucedanin hydrate is a furanocoumarin. It has a role as a metabolite.

(-)-Oxypeucedanin hydrate

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Purity: 99.99%

Catalog No. T5808Alias OXYPEUCEDANIN HYDRATECas No. 133164-11-1

(-)-Oxypeucedanin hydrate is a furanocoumarin. It has a role as a metabolite.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$98	-	In Stock
5 mg	$247	-	In Stock
10 mg	$372	-	In Stock
25 mg	$613	-	In Stock
1 mL x 10 mM (in DMSO)	$255	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.99%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	(-)-Oxypeucedanin hydrate is a furanocoumarin. It has a role as a metabolite.
In vitro	Oxypeucedanin exhibited marginal toxicity on normal fibroblast cells and sensitive parental mouse lymphoma cells;?furthermore, they were less toxic on multidrug resistant lymphoma cells.? Oxypeucedanin showed moderate MDR reversing activity.?In the checkerboard assay, oxypeucedanin and heraclenin showed slight synergistic effect with doxorubicin.?These compounds might improve the cytotoxic effect of the standard chemotherapeutic drug doxorubicin.
Cell Research	Pure compounds were isolated from the extract of aerial parts of the plant by chromatographic methods.Bioactivities were tested on multidrug resistant and sensitive mouse T-lymphoma cell lines.The inhibition of the cancer MDR efflux pump ABCB1 was evaluated by flow cytometry (at 2 and 20 μM).A checkerboard microplate method was applied to study the interactions of furocoumarins and doxorubicin.Toxicity was studied using normal murine NIH/3T3 fibroblasts.
Synonyms	OXYPEUCEDANIN HYDRATE

Chemical Properties

Molecular Weight	304.29
Formula	C₁₆H₁₆O₆
Cas No.	133164-11-1
Smiles	CC(C)(O)[C@@H](O)COc1c2ccoc2cc2oc(=O)ccc12
Relative Density.	1.386 g/cm3 (Predicted)

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (180.75 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.57 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2863 mL	16.4317 mL	32.8634 mL	164.3169 mL
5 mM	0.6573 mL	3.2863 mL	6.5727 mL	32.8634 mL
10 mM	0.3286 mL	1.6432 mL	3.2863 mL	16.4317 mL
20 mM	0.1643 mL	0.8216 mL	1.6432 mL	8.2158 mL
50 mM	0.0657 mL	0.3286 mL	0.6573 mL	3.2863 mL
100 mM	0.0329 mL	0.1643 mL	0.3286 mL	1.6432 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc