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Anti-Phospho-APP (Thr668) Polyclonal Antibody
(Synonyms: p-APP (Thr668), p-APP (T668), APP (p-Thr668), APP (p-T668)) Copy Product Info
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Synonyms: p-APP (Thr668), p-APP (T668), APP (p-Thr668), APP (p-T668)
Catalog No. TMAC-00249 Copy Product Info
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Anti-Phospho-APP (Thr668) Polyclonal Antibody is a Rabbit antibody targeting Phospho-APP (Thr668). Anti-Phospho-APP (Thr668) Polyclonal Antibody can be used in WB.
Anti-Phospho-APP
(Thr668) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $216 | 7-10 days | 7-10 days | |
| 100 µL | $317 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-Phospho-APP (Thr668) Polyclonal Antibody is a Rabbit antibody targeting Phospho-APP (Thr668). Anti-Phospho-APP (Thr668) Polyclonal Antibody can be used in WB. |
| Synonyms | p-APP (Thr668), p-APP (T668), APP (p-Thr668), APP (p-T668) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of extracts from mouse brain tissue using APP(Phospho-668) Antibody TMAC-00249(Lane 2) and the same antibody preincubated with blocking peptide(Lane1). 2. Western blot analysis of extracts from Hela cells, treated with Noc or calf intestinal phosphatase (CIP), using APP (Phospho-Thr668) Antibody TMAC-00249.  , |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | APP encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of threonine 668 (A-V-T(p)-P-E) derived from Human APP |
| Antigen Species | Human |
| Uniprot ID |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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