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UNC5B Protein, Human, Recombinant (hFc)

Catalog No. TMPY-00507
Synonyms: unc-5 homolog B (C. elegans), UNC5H2, p53RDL1

The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis.

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UNC5B Protein, Human, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 600.00
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Biological Description
Technical Params
Product Properties
Description The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis.
Species Human
Expression System HEK293
Tag hFc
Accession Number Q8IZJ1-1
Synonyms unc-5 homolog B (C. elegans), UNC5H2, p53RDL1
Construction A DNA sequence encoding the human UNC5B (NP_734465.2) (Met1-Pro363) was expressed with the Fc region of human IgG1 at the C-terminus.
Protein Purity > 90 % as determined by SDS-PAGE
Molecular Weight Approxiamtely 64.8 kDa
Endotoxin < 1.0 EU per μg protein as determined by the LAL method.
Formulation Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis.

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Keywords

UNC5B Protein, Human, Recombinant (hFc) C. elegans unc-5 homolog B (C. elegans) UNC5H2 p53RDL1 unc-5 homolog B recombinant recombinant-proteins proteins protein

 

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