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Anti-Carboxypeptidase B1 Antibody (8Y498)
😃Good
Catalog No. TMAY-00905
Alias carboxypeptidase B1 (tissue), AI504870, 2210008M23Rik, 1810063F02Rik, 0910001A18Rik
Anti-Carboxypeptidase B1 Antibody (8Y498) is a Mouse antibody targeting Carboxypeptidase B1. Anti-Carboxypeptidase B1 Antibody (8Y498) can be used in IHC-P.
Anti-Carboxypeptidase B1 Antibody (8Y498)
Anti-Carboxypeptidase B1 Antibody (8Y498)
😃Good
Catalog No. TMAY-00905Alias carboxypeptidase B1 (tissue), AI504870, 2210008M23Rik, 1810063F02Rik, 0910001A18Rik
Anti-Carboxypeptidase B1 Antibody (8Y498) is a Mouse antibody targeting Carboxypeptidase B1. Anti-Carboxypeptidase B1 Antibody (8Y498) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-Carboxypeptidase B1 Antibody (8Y498) is a Mouse antibody targeting Carboxypeptidase B1. Anti-Carboxypeptidase B1 Antibody (8Y498) can be used in IHC-P. |
| Alias | carboxypeptidase B1 (tissue), AI504870, 2210008M23Rik, 1810063F02Rik, 0910001A18Rik |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 8Y498 |
| Reactivity | Human |
| Verified Activity | Immunochemical staining of human CPB1 in human pancreas with mouse monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:1000-1:4000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Carboxypeptidase B1 / CPB1 (rh Carboxypeptidase B1 / CPB1; TMPY-00727; NP_001862.2; Met1-Tyr417). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Carboxypeptidase B1, also well known as pancreatic procarboxypeptidase B (PCPB), is a highly pancreas -specific protein (PASP), and has been identified previously as a serum marker for acute pancreatitis and pancreatic graft rejection. As the prototype for those human exopeptidases that cleave off basic C-terminal residues, CPB1 specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. The B1 and B2 forms of procarboxypeptidase B differ from each other mainly in isoelectric point.The deduced amino acid sequence of PCPB predicts a 416-amino acid preproenzyme consisting of a 15-aa signal peptide, a 95-aa activation peptide and a 37-aa mature chain. The secreted PCPB zymogen is converted to enzymatically active CPB1 by limited proteolysis by trypsin. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human Carboxypeptidase B1 / CPB1 protein (TMPY-00727) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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