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Anti-Carboxypeptidase B1 Antibody (8Y498) (Synonyms: carboxypeptidase B1 (tissue), AI504870, 2210008M23Rik, 1...)

Catalog No. TMAY-00905 Copy Product Info
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Anti-Carboxypeptidase B1 Antibody (8Y498) is a Mouse antibody targeting Carboxypeptidase B1. Anti-Carboxypeptidase B1 Antibody (8Y498) can be used in IHC-P.

Anti-Carboxypeptidase B1 Antibody (8Y498)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00905
Synonyms carboxypeptidase B1 (tissue), AI504870, 2210008M23Rik, 1810063F02Rik, 0910001A18Rik

Anti-Carboxypeptidase B1 Antibody (8Y498) is a Mouse antibody targeting Carboxypeptidase B1. Anti-Carboxypeptidase B1 Antibody (8Y498) can be used in IHC-P.

Anti-Carboxypeptidase B1 Antibody
(8Y498)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Carboxypeptidase B1 Antibody (8Y498) is a Mouse antibody targeting Carboxypeptidase B1. Anti-Carboxypeptidase B1 Antibody (8Y498) can be used in IHC-P.
Synonymscarboxypeptidase B1 (tissue), AI504870, 2210008M23Rik, 1810063F02Rik, 0910001A18Rik
Ig Type
Mouse IgG1
Clone
8Y498
Reactivity
Human
Specificity
Human Carboxypeptidase B1
No cross-reactivity in ELISA with
Human CPB1
Mouse CPB1
Human CPA1
Human CPA2
Human CPE
Verified Activity
Immunochemical staining of human CPB1 in human pancreas with mouse monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections).
Application
Recommended Dose
IHC-P: 1:1000-1:4000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Carboxypeptidase B1 / CPB1 (rh Carboxypeptidase B1 / CPB1; TMPY-00727; NP_001862.2; Met1-Tyr417). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCarboxypeptidase B1, also well known as pancreatic procarboxypeptidase B (PCPB), is a highly pancreas -specific protein (PASP), and has been identified previously as a serum marker for acute pancreatitis and pancreatic graft rejection. As the prototype for those human exopeptidases that cleave off basic C-terminal residues, CPB1 specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. The B1 and B2 forms of procarboxypeptidase B differ from each other mainly in isoelectric point.The deduced amino acid sequence of PCPB predicts a 416-amino acid preproenzyme consisting of a 15-aa signal peptide, a 95-aa activation peptide and a 37-aa mature chain. The secreted PCPB zymogen is converted to enzymatically active CPB1 by limited proteolysis by trypsin.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human Carboxypeptidase B1 / CPB1 protein (TMPY-00727)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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