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IRBP (1-20), human TFA, contains a prominent epitope recognized by the H-2b haplotype and is known to elicit experimental autoimmune uveoretinitis (EAU) in H-2b mouse models [1] [2].
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| Description | IRBP (1-20), human TFA, contains a prominent epitope recognized by the H-2b haplotype and is known to elicit experimental autoimmune uveoretinitis (EAU) in H-2b mouse models [1] [2]. |
| In vivo | IRBP (1-20), human TFA elicits EAU [2]. Lymph node and spleen cells, harvested 21 days post-immunization, are stimulated with the respective antigen to evaluate proliferative and cytokine responses. Both C57BL/6 and 129/J mouse cells proliferate upon stimulation with IRBP (1-20), human TFA [2]. |
| Molecular Weight | 2308.62 |
| Formula | C103H165F3N24O30S |
| Sequence | Gly-Pro-Thr-His-Leu-Phe-Gln-Pro-Ser-Leu-Val-Leu-Asp-Met-Ala-Lys-Val-Leu-Leu-Asp |
| Sequence Short | GPTHLFQPSLVLDMAKVLLD |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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