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GRGDSPC acetate (GRGDSPC acetate (91575-26-7 free base)) is a 7-amino acid peptide of thiolated cell adhesion.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $37 | In Stock | In Stock | |
| 5 mg | $115 | In Stock | In Stock | |
| 10 mg | $170 | In Stock | In Stock | |
| 25 mg | $308 | In Stock | In Stock | |
| 50 mg | $446 | In Stock | In Stock | |
| 100 mg | $630 | In Stock | In Stock | |
| 200 mg | $845 | In Stock | In Stock |
| Description | GRGDSPC acetate (GRGDSPC acetate (91575-26-7 free base)) is a 7-amino acid peptide of thiolated cell adhesion. |
| In vitro | Thiolated cell adhesion peptides (GRGDSPC) were conjugated to acrylated dextran via thiol-acrylate reaction to regulate the interactions of human mesenchymal stem cells (hMSCs) with the photocrosslinkable hydrogels. The hydrogels permitted sustained release of short interfering RNA (siRNA) over 7 weeks and were cytocompatible with hMSCs. Sustained presentation of siRNA from these photocrosslinked DEX hydrogels enhanced the osteogenic differentiation of encapsulated hMSCs. These DEX hydrogels with tunable siRNA delivery and cell adhesive properties may provide an excellent platform for bioactive molecule delivery and tissue regeneration applications. |
| Synonyms | GRGDSPC acetate(91575-26-7 free base), GRGDSPC |
| Molecular Weight | 750.78 |
| Formula | C27H46N10O13S |
| Smiles | CC(O)=O.SC[C@@H](C(O)=O)NC([C@H]1N(C([C@H](CO)NC([C@H](CC(O)=O)NC(CNC([C@H](CCCNC(N)=N)NC(CN)=O)=O)=O)=O)=O)CCC1)=O |
| Relative Density. | 1.31g/cm3 |
| Sequence | H-Gly-Arg-Gly-Asp-Ser-Pro-Cys-OH |
| Sequence Short | GRGDSPC |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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