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Anti-TFPI2 Antibody (8E995)
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Catalog No. TMAY-03514
Alias tissue factor pathway inhibitor 2, PP5/TFPI-2, AV000670
Anti-TFPI2 Antibody (8E995) is a Rabbit antibody targeting TFPI2. Anti-TFPI2 Antibody (8E995) can be used in ELISA,ELISA(Cap).
Anti-TFPI2 Antibody (8E995)
Anti-TFPI2 Antibody (8E995)
😃Good
Catalog No. TMAY-03514Alias tissue factor pathway inhibitor 2, PP5/TFPI-2, AV000670
Anti-TFPI2 Antibody (8E995) is a Rabbit antibody targeting TFPI2. Anti-TFPI2 Antibody (8E995) can be used in ELISA,ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $92 | 7-10 days | |
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA, ELISA(Cap) Reactivity: Mouse |
| Alias | tissue factor pathway inhibitor 2, PP5/TFPI-2, AV000670 |
| Ig Type | Rabbit IgG |
| Clone | 8E995 |
| Reactivity | Mouse |
| Application | ELISA,ELISA(Cap) |
| Recommended Dose | ELISA: 1:5000-1:10000; ELISA(Cap): 1:250-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TFPI2 (rM TFPI2; TMPY-02329; O35536; Met1-Lys211). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Tissue factor pathway inhibitor-2 (TFPI2), a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). It is a 32 kDa matrix-associated glycoprotein consisting of a short amino-terminal region, three tandem Kunitz-type domains and a positively charged carboxy-terminal tail. TFPI2 inhibits plasmin-dependent activation of several metalloproteinases. TFPI2 is highly abundant in the full-term placenta and widely expressed in various adult human tissues, such as the liver, skeletal muscle, heart, kidney, and pancreas. The expression of TFPI2 in tumors is inversely related to an increasing degree of malignancy, which may suggest a role for TFPI2 in the maintenance of tumor stability and inhibition of the growth of neoplasms. TFPI2 inhibits the tissue factor/factor VIIa (TF/VIIa) complex and a wide variety of serine proteinases including plasmin, plasma kallikrein, factor XIa, trypsin, and chymotrypsin. TFPI2 is involved in regulating pericellular proteases implicated in a variety of physiologic and pathologic processes including cancer cell invasion, vascular inflammation, and atherosclerosis. TFPI2 has also been shown to induce apoptosis and inhibit angiogenesis, which may contribute significantly to tumor growth inhibition. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse TFPI2 protein (TMPY-02329) |
| Antigen Species | Mouse |
| Biology Area | Serine Proteases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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