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Synonyms: Oxysterols receptor LXR-alpha, Nuclear receptor subfamily 1 group H member 3, NR1H3, LXRA, Liver X receptor alpha
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
| Description | Anti-LXR-alpha Antibody (5E494) is a Rabbit antibody targeting LXR-alpha. Anti-LXR-alpha Antibody (5E494) can be used in FCM,ICC,IHC,WB. |
| Synonyms | Oxysterols receptor LXR-alpha, Nuclear receptor subfamily 1 group H member 3, NR1H3, LXRA, Liver X receptor alpha |
| Ig Type | IgG |
| Clone | 5E494 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500; IHC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 50 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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