Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ProTx-II TFA is a potent and highly selective Nav1.7 sodium channel blocker, exhibiting an IC50 of 0.3 nM and demonstrating at least 100-fold selectivity over other sodium channel subtypes. It decreases channel conductance, shifts activation towards more positive potentials, and inhibits action potential propagation in nociceptors [1] [2].
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Description | ProTx-II TFA is a potent and highly selective Nav1.7 sodium channel blocker, exhibiting an IC50 of 0.3 nM and demonstrating at least 100-fold selectivity over other sodium channel subtypes. It decreases channel conductance, shifts activation towards more positive potentials, and inhibits action potential propagation in nociceptors [1] [2]. |
Molecular Weight | 3826.59 (free base) |
Formula | C168H250N46O41S8.xC2HF3O2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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ProTx II TFA Membrane transporter/Ion channel Sodium Channel inhibitor inhibit