IL-29 Protein, Human, Recombinant (E. coli)

Name: IL-29 Protein, Human, Recombinant (E. coli)
Brand: TargetMol
SKU: TMPS-00151
Rating: 4.5 (1 reviews)

(Synonyms: Interferon-λ1, IFNλ1) Copy Product Info

Synonyms: Interferon-λ1, IFNλ1

Catalog No. TMPS-00151 Copy Product Info

IL-29 Protein, Human, Recombinant (E. coli) is expressed in E. coli. The accession number is Q8IU54.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$163	7-10 days	7-10 days
10 µg	$263	7-10 days	7-10 days
20 µg	$428	7-10 days	7-10 days
50 µg	$819	7-10 days	7-10 days
100 µg	$1,350	7-10 days	7-10 days
200 µg	$1,890	7-10 days	7-10 days
500 µg	$2,970	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Fully biologically active when compared to standard. The ED50 as determined by an anti-viral assay using human HepG2 cells infected with encephalomyocarditis is less than 5.0 ng/ml, corresponding to a specific activity of > 2.0 × 10^5 IU/mg.
Description	IL-29 Protein, Human, Recombinant (E. coli) is expressed in E. coli. The accession number is Q8IU54.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	Q8IU54
Construction	Gly20-Thr200
Protein Purity	> 97% as determined by SDS-PAGE; > 97% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
Reconstitution	It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
Synonyms	Interferon-λ1, IFNλ1
Research Background	IL-28A, IL-28B, and IL-29, also named interferon-λ2 (IFN-λ2), IFN-λ3, and IFN-λ1, respectively, are newly identified class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11-13% aa sequence identity) and the type I IFN family (15-19% aa sequence identity). The expression of IL-28A, B, and IL-29 is induced by virus infection or double-stranded RNA. All three cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The three proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor β (IL-10 Rβ) and a novel IL-28 receptor α (IL-28 Rα, also known as IFN-λR1). Ligand binding to the receptor complex induces Jak kinase activation and STAT1 and STAT2 tyrosine phosphorylation.

Chemical Properties

Molecular Weight

19.8 kDa (Predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.