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Ethyl 4-amino-2-(methylthio)pyrimidine-5-carboxylate

🥰Excellent
Catalog No. T8621Cas No. 776-53-4

ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE used for preparation of pyrimidopyrimidines as protein kinase inhibitors.

Ethyl 4-amino-2-(methylthio)pyrimidine-5-carboxylate

Ethyl 4-amino-2-(methylthio)pyrimidine-5-carboxylate

🥰Excellent
Purity: 98.71%
Catalog No. T8621Cas No. 776-53-4
ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE used for preparation of pyrimidopyrimidines as protein kinase inhibitors.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$31In StockIn Stock
25 mg$54In StockIn Stock
50 mg$81In StockIn Stock
100 mg$120In StockIn Stock
500 mg$297-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.71%
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Product Introduction

Bioactivity
Description
ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE used for preparation of pyrimidopyrimidines as protein kinase inhibitors.
Chemical Properties
Molecular Weight213.26
FormulaC8H11N3O2S
Cas No.776-53-4
SmilesCCOC(=O)C1=CN=C(SC)N=C1N
Relative Density.1.31 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 27.5 mg/mL (128.95 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.6891 mL23.4456 mL46.8911 mL234.4556 mL
5 mM0.9378 mL4.6891 mL9.3782 mL46.8911 mL
10 mM0.4689 mL2.3446 mL4.6891 mL23.4456 mL
20 mM0.2345 mL1.1723 mL2.3446 mL11.7228 mL
50 mM0.0938 mL0.4689 mL0.9378 mL4.6891 mL
100 mM0.0469 mL0.2345 mL0.4689 mL2.3446 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ETHYL 4AMINO2(METHYLTHIO)PYRIMIDINE5CARBOXYLATEETHYL 4 AMINO 2 (METHYLTHIO)PYRIMIDINE 5 CARBOXYLATE
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