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FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

(Synonyms: TK25, TK14, K-SAM, KGFR, JWS, FLJ98662, FGFR2 α (IIIb), FGFR2 α, FGFR2 alpha, FGF R2a, ECT1, CFD1, CEK3, CD332, BFR-1, BEK, BBDS) Copy Product Info

Synonyms: TK25, TK14, K-SAM, KGFR, JWS, FLJ98662, FGFR2 α (IIIb), FGFR2 α, FGFR2 alpha, FGF R2a, ECT1, CFD1, CEK3, CD332, BFR-1, BEK, BBDS

Catalog No. TMPK-00401 Copy Product Info
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs.

Product Introduction

Bioactivity
Bioactivity
Immobilized Anti-FGFR2 alpha (IIIb) Antibody, hFc Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human FGFR2 alpha (IIIb) , His Tag with the EC50 of 20.3ng/ml determined by ELISA.
Description
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs.
Species
Human
Expression System
HEK293 Cells
TagC-His-Avi
Accession NumberP21802-3
ConstructionArg22-Glu378
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsTK25, TK14, K-SAM, KGFR, JWS, FLJ98662, FGFR2 α (IIIb), FGFR2 α, FGFR2 alpha, FGF R2a, ECT1, CFD1, CEK3, CD332, BFR-1, BEK, BBDS
Research Background
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs.
Chemical Properties
Molecular Weight42.5 kDa (predicted). Due to glycosylation, the protein migrates to 70-110 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated chemical structure | FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated molecular weight