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Fenpropidin

Name: Fenpropidin
Brand: TargetMol
SKU: T20691
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T20691Cas No. 67306-00-7

Alias Ro12-3049, Ro-12-3049, Ro 12-3049

Fenpropidin (Ro-12-3049), a fungicide, is a specific inhibitor of sterol 14-reductase and biosynthesis.

Fenpropidin

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Purity: 99.54%

Catalog No. T20691Alias Ro12-3049, Ro-12-3049, Ro 12-3049Cas No. 67306-00-7

Fenpropidin (Ro-12-3049), a fungicide, is a specific inhibitor of sterol 14-reductase and biosynthesis.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$31	-	In Stock
10 mg	$48	-	In Stock
25 mg	$64	In Stock	In Stock
50 mg	$77	In Stock	In Stock
100 mg	$123	-	In Stock
200 mg	$179	-	In Stock
500 mg	$297	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.54%

Appearance:Liquid

Color:Transparent

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COA LCMS GC

Product Introduction

Fenpropidin AI Summary

Fenpropidin exhibits a range of bioactivities, including inhibition of various enzymatic and microbial targets. It is an inhibitor of Polymerase Kappa with a potency of 29934.9 nM. In Zea mays (maize), it inhibits delta8,delta7-sterol isomerase (IC50 = 80.0 nM), cycloeucalenol-obtusifolial isomerase (IC50 = 200.0 nM), and microsomal delta 8,14-steroid 14-reductase (IC50 = 3000.0 nM). Despite no antifungal activity against Blumeria graminis in wheat plants at 500 ug/ml, it shows antifungal activity against strains like Candida albicans, Cryptococcus neoformans, Candida glabrata, Candida tropicalis, and Aspergillus niger, with varying IC50, MIC, and MFC values. Additionally, it displays antiviral activity against SARS-CoV-2 with an IC50 value greater than 20000.0 nM, indicating relatively low potency. The compound has also been tested for metabolic stability, showing low degradation rates in mouse and human liver microsomes..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Fenpropidin (Ro-12-3049), a fungicide, is a specific inhibitor of sterol 14-reductase and biosynthesis.
Synonyms	Ro12-3049, Ro-12-3049, Ro 12-3049

Chemical Properties

Molecular Weight	273.46
Formula	C₁₉H₃₁N
Cas No.	67306-00-7
Smiles	C(C(CN1CCCCC1)C)C2=CC=C(C(C)(C)C)C=C2
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (182.84 mM), Sonication is recommended.

H2O: 0.53 mg/mL (1.94 mM), when pH is adjusted to 7.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6568 mL	18.2842 mL	36.5684 mL	182.8421 mL

DMSO

	1mg	5mg	10mg	50mg
5 mM	0.7314 mL	3.6568 mL	7.3137 mL	36.5684 mL
10 mM	0.3657 mL	1.8284 mL	3.6568 mL	18.2842 mL
20 mM	0.1828 mL	0.9142 mL	1.8284 mL	9.1421 mL
50 mM	0.0731 mL	0.3657 mL	0.7314 mL	3.6568 mL
100 mM	0.0366 mL	0.1828 mL	0.3657 mL	1.8284 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc