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Anti-ORP150 Antibody (6L921)
(Synonyms: ORP-150, ORP150, hypoxia up-regulated 1, HSP12A, GRP-170) Copy Product Info
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Synonyms: ORP-150, ORP150, hypoxia up-regulated 1, HSP12A, GRP-170
Catalog No. TMAY-01846 Copy Product Info
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Anti-ORP150 Antibody (6L921) is a Rabbit antibody targeting ORP150. Anti-ORP150 Antibody (6L921) can be used in ELISA,ICC/IF,IHC-P,IP,WB.
Anti-ORP150 Antibody
(6L921)
(6L921)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $268 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ORP150 Antibody (6L921) is a Rabbit antibody targeting ORP150. Anti-ORP150 Antibody (6L921) can be used in ELISA,ICC/IF,IHC-P,IP,WB. |
| Synonyms | ORP-150, ORP150, hypoxia up-regulated 1, HSP12A, GRP-170 |
| Ig Type | Rabbit IgG |
| Clone | 6L921 |
| Reactivity | Human |
| Specificity | Human ORP150 No cross-reactivity in ELISA with Human Fetuin A |
| Application | |
| Recommended Dose | WB: 1:500-1:2000; ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500; ICC-IF: 1:20-1:100; IP: 1-4 μL/mg of lysate |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ORP150 / HYOU1 / HSP12A (rh ORP150 / HYOU1 / HSP12A; TMPY-01577; NP_001124463.1; Met 695-Leu 994). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Hypoxia up-regulated protein 1, also known as 15 kDa oxygen-regulated protein, 17 kDa glucose-regulated protein, ORP-15, GRP-17, and HYOU1, is a member of the heat shock protein 7 family. Seven members from four different heat shock protein (HSP) families were identified including HYOU1 (ORP15), HSPC1 (HSP86), HSPA5 (Bip), HSPD1 (HSP6), and several isoforms of the two testis-specific HSP7 chaperones HSPA2 and HSPA1L. HYOU1 is highly expressed in tissues that contain well-developed endoplasmic reticulum and synthesize large amounts of secretory proteins. It is highly expressed in the liver and pancreas. HYOU1 is also expressed in macrophages within aortic atherosclerotic plaques and in breast cancers. HYOU1 has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. It may play a role as a molecular chaperone and participate in protein folding. Suppression of HYOU1 is associated with accelerated apoptosis. It is suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein is up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human ORP150 / HYOU1 / HSP12A protein (TMPY-01577) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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