Claudin-6 Protein, Human, Recombinant, Fluorescent,VLP

Catalog No. TMPY-06766

Claudin-6 Protein, Human, Recombinant, Fluorescent,VLP is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.31 kDa and the accession number is P56747.

Claudin-6 Protein, Human, Recombinant, Fluorescent,VLP

Catalog No. TMPY-06766

Claudin-6 Protein, Human, Recombinant, Fluorescent,VLP is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.31 kDa and the accession number is P56747.

Pack Size	Price	Availability
5 μg	$298	7-10 days
10 μg	$490	7-10 days
20 μg	$838	7-10 days
50 μg	$1,230	7-10 days
100 μg	$1,930	7-10 days
200 μg	$2,750	7-10 days
500 μg	$6,150	7-10 days

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Product Information

Biological Activity	Immobilized Human CLDN6-VLP (Full Length) Protein at 5 μg/mL (100 μL/well) can bind Anti-Human CLDN6 Antibody, Human IgG1, the EC50 is 5-25 ng/mL.
Description	Claudin-6 Protein, Human, Recombinant, Fluorescent,VLP is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.31 kDa and the accession number is P56747.
Species	Human
Expression System	HEK293 Cells
Tag	Tag Free
Accession Number	P56747
Synonyms	claudin 6
Construction	A DNA sequence encoding the human CLDN6 (P56747) (Met1-Val220) was expressed. This protein carries a GFP tag. Predicted N terminal: Met 1
Molecular Weight	50.31 kDa (predicted)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as solution in 50 mM HEPES, 150 mM NaCI, 10% Trehalose, pH 7.2.
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Shipping with blue ice.
Research Background	Claudin-6 (CLDN6) belongs to the claudins family and is a transmembrane protein found in tight junctions with two extracellular loops and intracellular N and C tails. CLDN6 modulates the ion- and charge-specific permeability of the paracellular pathway in most epithelial tissues. It regulates the paracellular flux of cations in the kidney through forming heterotypic strands with other claudins and has a role in maintaining the lung epithelial barrier function. The CLDN6 gene is adjacent to another family member, CLDN9, on chromosome 16. Certain CLDN6-positive cancers, encompassing ovarian, endometrial, and testicular malignancies, have been shown to have their proliferation and invasiveness suppressed upon CLDN6 silencing.