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Claudin-6 Protein, Human, Recombinant, Fluorescent,VLP

(Synonyms: claudin 6) Copy Product Info

Synonyms: claudin 6

Catalog No. TMPY-06766 Copy Product Info
Claudin-6 Protein, Human, Recombinant, Fluorescent,VLP is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.31 kDa and the accession number is P56747.
Pack SizePriceUSA StockGlobal StockQuantity
10 µg$4907-10 days7-10 days
20 µg$8387-10 days7-10 days
50 µg$1,2307-10 days7-10 days
100 µg$1,9307-10 days7-10 days
200 µg$2,7507-10 days7-10 days
500 µg$6,1507-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Human CLDN6-VLP (Full Length) Protein at 5 μg/mL (100 μL/well) can bind Anti-Human CLDN6 Antibody, Human IgG1, the EC50 is 5-25 ng/mL.
Description
Claudin-6 Protein, Human, Recombinant, Fluorescent,VLP is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.31 kDa and the accession number is P56747.
Species
Human
Expression System
HEK293 Cells
TagTag Free
Accession NumberP56747
ConstructionA DNA sequence encoding the human CLDN6 (P56747) (Met1-Val220) was expressed. This protein carries a GFP tag. Predicted N terminal: Met 1
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as solution in 50 mM HEPES, 150 mM NaCI, 10% Trehalose, pH 7.2.
Synonymsclaudin 6
Research Background
Claudin-6 (CLDN6) belongs to the claudins family and is a transmembrane protein found in tight junctions with two extracellular loops and intracellular N and C tails. CLDN6 modulates the ion- and charge-specific permeability of the paracellular pathway in most epithelial tissues. It regulates the paracellular flux of cations in the kidney through forming heterotypic strands with other claudins and has a role in maintaining the lung epithelial barrier function. The CLDN6 gene is adjacent to another family member, CLDN9, on chromosome 16. Certain CLDN6-positive cancers, encompassing ovarian, endometrial, and testicular malignancies, have been shown to have their proliferation and invasiveness suppressed upon CLDN6 silencing.
Chemical Properties
Molecular Weight50.31 kDa (predicted)
Storage & Solubility Information
ShippingProteins are shipped with blue ice.
StorageIt is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: Claudin-6 Protein, Human, Recombinant, Fluorescent,VLP chemical structure | Claudin-6 Protein, Human, Recombinant, Fluorescent,VLP molecular weight