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p-Aminobenzamidine dihydrochloride

🥰Excellent
Catalog No. T60248Cas No. 2498-50-2
Alias p-Aminobenzamidine dihydrochloride

4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type plasminogen activator (uPA) (K i =82 μM). 4-Aminobenzamidine can inhibit growth of a human prostate tumor in SCID mice [1] [2].

p-Aminobenzamidine dihydrochloride

p-Aminobenzamidine dihydrochloride

🥰Excellent
Purity: 99.56%
Catalog No. T60248Alias p-Aminobenzamidine dihydrochlorideCas No. 2498-50-2
4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type plasminogen activator (uPA) (K i =82 μM). 4-Aminobenzamidine can inhibit growth of a human prostate tumor in SCID mice [1] [2].
Pack SizePriceAvailabilityQuantity
2 g$32In Stock
5 g$68In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Batch Information

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Purity:99.56%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type plasminogen activator (uPA) (K i =82 μM). 4-Aminobenzamidine can inhibit growth of a human prostate tumor in SCID mice [1] [2].
Synonymsp-Aminobenzamidine dihydrochloride
Chemical Properties
Molecular Weight208.088
FormulaC7H11Cl2N3
Cas No.2498-50-2
SmilesCl.Cl.NC(=N)C1=CC=C(N)C=C1
ColorYellow
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (240.28 mM), Sonication and heating to 80℃ are recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (4.81 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.8057 mL24.0283 mL48.0566 mL240.2830 mL
5 mM0.9611 mL4.8057 mL9.6113 mL48.0566 mL
10 mM0.4806 mL2.4028 mL4.8057 mL24.0283 mL
20 mM0.2403 mL1.2014 mL2.4028 mL12.0141 mL
50 mM0.0961 mL0.4806 mL0.9611 mL4.8057 mL
100 mM0.0481 mL0.2403 mL0.4806 mL2.4028 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TrypsinSerineProteaseSerine Proteasep-Aminobenzamidine Dihydrochloridep-Aminobenzamidine4-Aminobenzamidine Dihydrochloride4-Aminobenzamidine
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