Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-PD-L1 Antibody (4R62)
(Synonyms: PD-L1B7 homolog 1, PD-L1, PDL1, PDCD1LG1, PDCD1L1, CD274, B7-H1, B7H1, B7-H) Copy Product Info
🥰Excellent
Synonyms: PD-L1B7 homolog 1, PD-L1, PDL1, PDCD1LG1, PDCD1L1, CD274, B7-H1, B7H1, B7-H
Catalog No. TMAH-00185 Copy Product Info
🥰Excellent
Anti-PD-L1 Antibody (4R62) is an antibody targeting PD-L1. Anti-PD-L1 Antibody (4R62) can be used in ELISA,IHC,WB.
Anti-PD-L1 Antibody
(4R62)
(4R62)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-PD-L1 Antibody (4R62) is an antibody targeting PD-L1. Anti-PD-L1 Antibody (4R62) can be used in ELISA,IHC,WB. |
| Synonyms | PD-L1B7 homolog 1, PD-L1, PDL1, PDCD1LG1, PDCD1L1, CD274, B7-H1, B7H1, B7-H |
| Ig Type | Rabbit IgG |
| Clone | 4R62 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. Recycling endosome membrane; Single-pass type I membrane protein.; [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Endomembrane system; Single-pass type I membrane protein. |
| Tissue Specificity | Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10). The PDCD1-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and escape destruction by the immune system, thereby facilitating tumor survival. The interaction with PDCD1/PD-1 inhibits cytotoxic T lymphocytes (CTLs) effector function. The blockage of the PDCD1-mediated pathway results in the reversal of the exhausted T-cell phenotype and the normalization of the anti-tumor response, providing a rationale for cancer immunotherapy. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human PD-L1 (CD274) |
| Antigen Species | Human |
| Gene Name | CD274 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer, Immunology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
Preview
Related Tags:
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.