ULBP-2 Protein, Human, Recombinant (His)

Name: ULBP-2 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-02333
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: UNQ463 / PRO791, UL16 binding protein 2, RAET1H, NKG2DL2, N2DL2, ALCAN-α, ALCAN-alpha) Copy Product Info

Synonyms: UNQ463 / PRO791, UL16 binding protein 2, RAET1H, NKG2DL2, N2DL2, ALCAN-α, ALCAN-alpha

Catalog No. TMPY-02333 Copy Product Info

Purity: 99.1%

ULBP-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.2 kDa and the accession number is Q9BZM5.

Pack Size	Price	USA Stock	Global Stock
5 µg	$48	-	In Stock
10 µg	$75	-	In Stock
20 µg	$118	-	In Stock
50 µg	$229	-	In Stock
100 µg	$386	-	In Stock
200 µg	$682	7-10 days	7-10 days
500 µg	$1,430	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.1%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Loaded Recombinant Human ULBP2 Protein, His Tag (Cat#TMPY-02333) on NTA Biosensor, can bind Recombinant Human NKG2D Protein, mFc Tag (Cat#TMPY-06827) with an affinity constant of 0.247 µM as determined in BLI assay (Sartorius Octet RED384) (QC tested).
Description	ULBP-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.2 kDa and the accession number is Q9BZM5.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q9BZM5
Construction	A DNA sequence encoding the human ULBP2 (Q9BZM5) (Met 1-Ser 217), without the pro peptide, was fused with a polyhistidine tag at the C-terminus. Predicted N terminal: Gly 26
Protein Purity	> 97 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	UNQ463 / PRO791, UL16 binding protein 2, RAET1H, NKG2DL2, N2DL2, ALCAN-α, ALCAN-alpha
Research Background	NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. ULBP2 / N2DL-2 is a ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway.

Chemical Properties

Molecular Weight

23.2 kDa (predicted); 33 kDa (reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.