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Anti-Phospho-HER2/ERBB2 (Tyr1139) Polyclonal Antibody

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Catalog No. TMAC-01801

Anti-Phospho-HER2/ERBB2 (Tyr1139) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HER2/ERBB2 (Tyr1139). Anti-Phospho-HER2/ERBB2 (Tyr1139) Polyclonal Antibody can be used in IHC-P,IF(paraffin section),WB.

Anti-Phospho-HER2/ERBB2 (Tyr1139) Polyclonal Antibody

Anti-Phospho-HER2/ERBB2 (Tyr1139) Polyclonal Antibody

😃Good
Catalog No. TMAC-01801
Anti-Phospho-HER2/ERBB2 (Tyr1139) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HER2/ERBB2 (Tyr1139). Anti-Phospho-HER2/ERBB2 (Tyr1139) Polyclonal Antibody can be used in IHC-P,IF(paraffin section),WB.
Pack SizePriceAvailabilityQuantity
50 μL$2187-10 days
100 μL$3177-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-HER2/ERBB2 (Tyr1139) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HER2/ERBB2 (Tyr1139). Anti-Phospho-HER2/ERBB2 (Tyr1139) Polyclonal Antibody can be used in IHC-P,IF(paraffin section),WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
IHC-P 1:50-200 WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
AppearanceLiquid
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research Backgrounderb-b2 receptor tyrosine kinase 2(ERBB2) Homo sapiens This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding d
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human HER2 around the phosphorylation site of Tyr1139
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 180 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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