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Anti-AP2 beta Antibody (6Y40)
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Catalog No. TMAC-00231
Alias Transcription factor AP-2-beta, Transcription factor AP2 beta, Transcription factor AP 2 beta, Tfap2b, TFAP 2B, PDA2, OTTHUMP00000039925, MGC21381, AP2β, AP2-beta, AP2beta, AP2B_HUMAN, AP2B, AP2 β, AP2 B, AP 2B, Activating enhancer-binding protein 2-beta, Activating enhancer binding protein 2 beta
Anti-AP2 beta Antibody (6Y40) is a Mouse antibody targeting AP2 beta. Anti-AP2 beta Antibody (6Y40) can be used in WB,FCM.
Anti-AP2 beta Antibody (6Y40)
Anti-AP2 beta Antibody (6Y40)
😃Good
Catalog No. TMAC-00231Alias Transcription factor AP-2-beta, Transcription factor AP2 beta, Transcription factor AP 2 beta, Tfap2b, TFAP 2B, PDA2, OTTHUMP00000039925, MGC21381, AP2β, AP2-beta, AP2beta, AP2B_HUMAN, AP2B, AP2 β, AP2 B, AP 2B, Activating enhancer-binding protein 2-beta, Activating enhancer binding protein 2 beta
Anti-AP2 beta Antibody (6Y40) is a Mouse antibody targeting AP2 beta. Anti-AP2 beta Antibody (6Y40) can be used in WB,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $428 | 7-10 days |
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| Description | Anti-AP2 beta Antibody (6Y40) is a Mouse antibody targeting AP2 beta. Anti-AP2 beta Antibody (6Y40) can be used in WB,FCM. |
| Synonyms | Transcription factor AP-2-beta, Transcription factor AP2 beta, Transcription factor AP 2 beta, Tfap2b, TFAP 2B, PDA2, OTTHUMP00000039925, MGC21381, AP2β, AP2-beta, AP2beta, AP2B_HUMAN, AP2B, AP2 β, AP2 B, AP 2B, Activating enhancer-binding protein 2-beta, Activating enhancer binding protein 2 beta |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of AP2 beta on human AP2 beta recombinant protein using anti- AP2 beta antibody at 1/1,000 dilution. 2. Western blot analysis of AP2 beta on HEK293 (1) and AP2 beta -hIgGFc transfected HEK293 (2) cell lysate using anti- AP2 beta antibody at 1/1,000 dilution. 3. Western blot analysis of AP2 beta on SK-N-SH cell lysate using anti- AP2 beta antibody at 1/1,000 dilution. 4. Flow cytometric analysis of SK-N-SH cells with AP2 beta antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1:100-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | AP-2 transcription factor family members include AP-2α, AP-2β and AP-2γ, which specifically bind to the DNA consensus sequence CCCCAGGC and initiate transcription of selected genes. AP-2, also known as ERF-1, plays a role in regulating estrogen receptor expression. AP-2β, a splice variant of AP-2α, inhibits AP-2 activity. Besides subscribing to the AP-2 complex, AP-2α, AP-2β and AP-2γ proteins compose the OB2-1 transcription factor complex. OB2-1 specifically upregulates expression of the proto-oncogene c-ErbB-2, which is overexpressed in 25-30% of breast cancers. AP-2α may play an important role in the development of ectodermal-derived tissues. Deleterious mutations involving the AP-2α gene are linked to microphthalmia, corneal clouding and other anterior eye chamber defects. The ubiquitously expressed AP-4 transcription factor specifically binds to the DNA consensus sequence 5'-CAGCTG-3'. AP-4 interacts with promoters for immunoglobulin-κ gene families and simian virus 40. AP-4 may enhance the transcription of the human Huntington's disease gene. AP-4 is a helix-loop-helix protein that contains two distinctive leucine repeat elements. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 50 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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