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Anti-AP2 beta Antibody (6Y40)

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Catalog No. TMAC-00231

Anti-AP2 beta Antibody (6Y40) is a Mouse antibody targeting AP2 beta. Anti-AP2 beta Antibody (6Y40) can be used in WB,FCM.

Anti-AP2 beta Antibody (6Y40)

Anti-AP2 beta Antibody (6Y40)

😃Good
Catalog No. TMAC-00231
Anti-AP2 beta Antibody (6Y40) is a Mouse antibody targeting AP2 beta. Anti-AP2 beta Antibody (6Y40) can be used in WB,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4287-10 days
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Product Introduction

Bioactivity
Description
Anti-AP2 beta Antibody (6Y40) is a Mouse antibody targeting AP2 beta. Anti-AP2 beta Antibody (6Y40) can be used in WB,FCM.
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000; FCM: 1:100-200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundAP-2 transcription factor family members include AP-2α, AP-2β and AP-2γ, which specifically bind to the DNA consensus sequence CCCCAGGC and initiate transcription of selected genes. AP-2, also known as ERF-1, plays a role in regulating estrogen receptor expression. AP-2β, a splice variant of AP-2α, inhibits AP-2 activity. Besides subscribing to the AP-2 complex, AP-2α, AP-2β and AP-2γ proteins compose the OB2-1 transcription factor complex. OB2-1 specifically upregulates expression of the proto-oncogene c-ErbB-2, which is overexpressed in 25-30% of breast cancers. AP-2α may play an important role in the development of ectodermal-derived tissues. Deleterious mutations involving the AP-2α gene are linked to microphthalmia, corneal clouding and other anterior eye chamber defects. The ubiquitously expressed AP-4 transcription factor specifically binds to the DNA consensus sequence 5'-CAGCTG-3'. AP-4 interacts with promoters for immunoglobulin-κ gene families and simian virus 40. AP-4 may enhance the transcription of the human Huntington's disease gene. AP-4 is a helix-loop-helix protein that contains two distinctive leucine repeat elements.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 50 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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