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Anti-Phospho-p63 (Ser395) Polyclonal Antibody
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Catalog No. TMAC-03011
Anti-Phospho-p63 (Ser395) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p63 (Ser395). Anti-Phospho-p63 (Ser395) Polyclonal Antibody can be used in WB.
Anti-Phospho-p63 (Ser395) Polyclonal Antibody
Anti-Phospho-p63 (Ser395) Polyclonal Antibody
😃Good
Catalog No. TMAC-03011
Anti-Phospho-p63 (Ser395) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p63 (Ser395). Anti-Phospho-p63 (Ser395) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $217 | 7-10 days | |
| 100 μL | $317 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-Phospho-p63 (Ser395) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p63 (Ser395). Anti-Phospho-p63 (Ser395) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-3000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 395 (R-R-S(p)-P-D) derived from Human p63 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 77 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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