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Anti-Phospho-p63 (Ser395) Polyclonal Antibody

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Catalog No. TMAC-03011

Anti-Phospho-p63 (Ser395) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p63 (Ser395). Anti-Phospho-p63 (Ser395) Polyclonal Antibody can be used in WB.

Anti-Phospho-p63 (Ser395) Polyclonal Antibody

Anti-Phospho-p63 (Ser395) Polyclonal Antibody

😃Good
Catalog No. TMAC-03011
Anti-Phospho-p63 (Ser395) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p63 (Ser395). Anti-Phospho-p63 (Ser395) Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2177-10 days
100 μL$3177-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-p63 (Ser395) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p63 (Ser395). Anti-Phospho-p63 (Ser395) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-3000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundActs as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine 395 (R-R-S(p)-P-D) derived from Human p63
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 77 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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