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FGF-21 Protein, Human, Recombinant (Low Endotoxin)
(Synonyms: UNQ3115 / PRO10196, fibroblast growth factor 21) Copy Product InfoSynonyms: UNQ3115 / PRO10196, fibroblast growth factor 21
Catalog No. TMPY-06935 Copy Product Info
Purity: 96.5%
FGF-21 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.55 kDa and the accession number is NP_061986.1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $50 | - | In Stock | |
| 10 µg | $79 | 7-10 days | 7-10 days | |
| 20 µg | $127 | - | In Stock | |
| 50 µg | $245 | - | In Stock | |
| 100 µg | $435 | 7-10 days | 7-10 days | |
| 200 µg | $770 | 7-10 days | 7-10 days | |
| 500 µg | $1,630 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
Batch Information
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Purity:96.5%
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Measured in a cell proliferation assay using NIH-3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.1-0.6 µg/mL in the presence of Recombinant Mouse Klotho beta. |
| Description | FGF-21 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.55 kDa and the accession number is NP_061986.1. |
| Species | Human |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | NP_061986.1 |
| Construction | A DNA sequence encoding the Human FGF21 (NP_061986.1) (His29-Ser209) was expressed. Predicted N terminal: Met |
| Protein Purity | ≥ 95 % as determined by SDS-PAGE.  |
| Endotoxin | < 10 EU/mg of the protein. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 0.63 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Synonyms | UNQ3115 / PRO10196, fibroblast growth factor 21 |
| Research Background | Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. The metabolic regulator fibroblast growth factor 21 (FGF21) has antidiabetic properties in animal models of diabetes and obesity. FGF21 is a novel adipokine associated with obesity-related metabolic complications in humans. The paradoxical increase of serum FGF21 in obese individuals, which may be explained by a compensatory response or resistance to FGF21, warrants further investigation. FGF-21, which we have identified as a novel metabolic factor, exhibits the therapeutic characteristics necessary for an effective treatment of diabetes. |
| Molecular Weight | 19.55 kDa (predicted); 22.4 kDa (reducing conditions) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: FGF-21 Protein, Human, Recombinant (Low Endotoxin) chemical structure | FGF-21 Protein, Human, Recombinant (Low Endotoxin) molecular weight
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