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PF-06342674
(Synonyms: RN-168, RN168, PF06342674) Copy Product Info
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Synonyms: RN-168, RN168, PF06342674
Catalog No. T77425 Copy Product Info
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PF-06342674 is a humanized monoclonal antibody targeting the IL-7 receptor-α, with immunoregulatory activity, used in Type 1 diabetes research.
PF-06342674
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $197 | - | In Stock | |
| 5 mg | $596 | - | In Stock | |
| 10 mg | $953 | - | In Stock | |
| 25 mg | $1,390 | - | In Stock | |
| 50 mg | $1,880 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.69% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | PF-06342674 is a humanized monoclonal antibody targeting the IL-7 receptor-α, with immunoregulatory activity, used in Type 1 diabetes research. |
| Targets & IC50 | IL-7Ra/CD127:34.14 ng/mL (EC50) |
| Synonyms | RN-168, RN168, PF06342674 |
| Reactivity | Human |
| Verified Activity | Immobilized Human IL-7Rα Protein (ECD, His) at 2 μg/mL can bind PF-06342674. The EC50 is 0.03414 μg/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | IL-7Ra/CD127 |
| Molecular Weight | 145.14 kDa |
| Smiles | #N/A |
| Isotype | Human IgG1 lambda2 |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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