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PF-06342674 (Synonyms: RN-168, RN168, PF06342674)

Catalog No. T77425 Copy Product Info
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PF-06342674 is a humanized monoclonal antibody targeting the IL-7 receptor-α, with immunoregulatory activity, used in Type 1 diabetes research.

PF-06342674

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Catalog No. T77425
Synonyms RN-168, RN168, PF06342674

PF-06342674 is a humanized monoclonal antibody targeting the IL-7 receptor-α, with immunoregulatory activity, used in Type 1 diabetes research.

PF-06342674
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$197-In Stock
5 mg$596-In Stock
10 mg$953-In Stock
25 mg$1,390-In Stock
50 mg$1,880-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.69% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
PF-06342674 is a humanized monoclonal antibody targeting the IL-7 receptor-α, with immunoregulatory activity, used in Type 1 diabetes research.
Targets&IC50
IL-7Ra/CD127:34.14 ng/mL (EC50)
SynonymsRN-168, RN168, PF06342674
Reactivity
Human
Verified Activity
Immobilized Human IL-7Rα Protein (ECD, His) at 2 μg/mL can bind PF-06342674. The EC50 is 0.03414 μg/mL.
verifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetIL-7Ra/CD127
Chemical Properties
Molecular Weight145.14 kDa
Smiles#N/A
Antibody Information
IsotypeHuman IgG1 lambda2
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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