Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SHP2-IN-14 (compound 27) is a potent, orally active allosteric inhibitor of SHP2, displaying strong anti-tumor activity with an IC50 of 7 nM. It inhibits tumor progression in NCI-H358 tumor-bearing mice and demonstrates favorable pharmacokinetic properties and safety [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 1,970.00 | |
50 mg | 8-10 weeks | $ 2,580.00 | |
100 mg | 8-10 weeks | $ 3,400.00 |
Description | SHP2-IN-14 (compound 27) is a potent, orally active allosteric inhibitor of SHP2, displaying strong anti-tumor activity with an IC50 of 7 nM. It inhibits tumor progression in NCI-H358 tumor-bearing mice and demonstrates favorable pharmacokinetic properties and safety [1]. |
Molecular Weight | 483.35 |
Formula | C22H20Cl2N8O |
CAS No. | 2673400-91-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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SHP2-IN-14 2673400-91-2 inhibitor inhibit