Others

Expression system: HEK293 Cells
Length: 20-340, Extracellular Domain
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-493, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-393, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 2-352, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 29-500, Full Length of Mature Protein
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 2-624, Partial
Activity: Not Tested

SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. SERPINB3 is expressed in some hepatocellular carcinoma (at protein level). Its expression is closely related to cellular differentiation in both normal and malignant squamous cells. It seems to also be secreted in plasma by cancerous cells but at a low level. SERPINB3 significantly attenuates apoptosis by contrasting cytochrome c release from the mitochondria and by antichemotactic effect for NK cells. It may act as a protease inhibitor to modulate the host immune response against tumor cells and may be involved in the malignant behavior of squamous cell carcinoma cells.

Expression system: HEK293 Cells
Length: 12-86, Full Length of Mature Protein
Activity: ELISA

Expression system: HEK293 Cells
Length: 22-339, Partial
Activity: ELISA

Expression system: Baculovirus Insect Cells
Length: 500-1229, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-145, Full Length
Activity: Enzyme Activity

Expression system: P. pastoris (Yeast)
Length: 22-418, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 1-273, Full Length
Activity: Not Tested

S100A8 & S100A9 Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in Baculovirus insect cells with Flag and His tag. The predicted molecular weight is 12.2 kDa and the accession number is NP_002955.2&NP_002956.1.

AIM2, Absent In Melanoma 2 is a member of the interferon-inducible HIN-200 protein family that contains an amino-terminal pyrin domain and a carboxy-terminal oligonucleotide oligosaccharide-binding domain, senses cytoplasmic DNA by means of its oligonucleotide oligosaccharide-binding domain and interacts with ASC (apoptosis-associated speck-like protein containing a CARD) through its pyrin domain to activate caspase-1. In response to foreign cytoplasmic DNA, AIM2 forms an inflammasome, resulting in caspase activation in inflammatory cells. It had been pointed to a role of AIM2 function in both inflammation and cancer. AIM-2 antigen is expressed in a wide variety of tumor types, including neuroectodermal tumors, as well as breast, ovarian and colon carcinomas. AIM-2 could be used as a tumor antigen target for monitoring vaccine trials or to develop antigen specific active immunotherapy for glioma patients.

Expression system: E. coli
Length: 1-320, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 2- 356, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 2-339, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-439, Full Length
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-245, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 2-339, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 1-526, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 19-160, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 1253-1497, Partial
Activity: Not Tested