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Anti-TLR7 Polyclonal Antibody

😃Good
Catalog No. TMAB-01859

Anti-TLR7 Polyclonal Antibody is a Rabbit antibody targeting TLR7. Anti-TLR7 Polyclonal Antibody can be used in WB.

Anti-TLR7 Polyclonal Antibody

Anti-TLR7 Polyclonal Antibody

😃Good
Catalog No. TMAB-01859
Anti-TLR7 Polyclonal Antibody is a Rabbit antibody targeting TLR7. Anti-TLR7 Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$220 7-10 days
100 μL$373 7-10 days
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Product Introduction

Bioactivity
Description
Anti-TLR7 Polyclonal Antibody is a Rabbit antibody targeting TLR7. Anti-TLR7 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human
Verified Activity
Sample:
Lane 1: Human THP-1 (LPS) cell lysates
Lane 2: Human THP-1 cell lysates
Lane 3: Human Jurkat cell lysates
Lane 4: Human MCF-7 cell lysates
Lane 5: Human 293T cell lysates
Primary: Anti-TLR7 (TMAB-01859) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 121 kDa
Observed band size: 65,121 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundKey component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human TLR7
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Developmental Families,Receptors,Macrophage / Inflamm.,TLR Signaling,Transmembrane
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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