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Anti-Alpha actinin Antibody (8E638)
😃Good
Catalog No. TMAB-00103
Alias Non-Muscle alpha-Actinin-1, FLJ54432, FLJ40884, F-Actin Cross-Linking Protein, BDPLT15, alpha-actinin-1, alpha-actinin cytoskeletal isoform, alpha Actinin 1, ACTN1, ACTN 1, Actinin, alpha 1, Actinin alpha 1, Actinin 1 Smooth Muscle
Anti-Alpha actinin Antibody (8E638) is a Mouse antibody targeting Alpha actinin. Anti-Alpha actinin Antibody (8E638) can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P.
Anti-Alpha actinin Antibody (8E638)
Anti-Alpha actinin Antibody (8E638)
😃Good
Catalog No. TMAB-00103Alias Non-Muscle alpha-Actinin-1, FLJ54432, FLJ40884, F-Actin Cross-Linking Protein, BDPLT15, alpha-actinin-1, alpha-actinin cytoskeletal isoform, alpha Actinin 1, ACTN1, ACTN 1, Actinin, alpha 1, Actinin alpha 1, Actinin 1 Smooth Muscle
Anti-Alpha actinin Antibody (8E638) is a Mouse antibody targeting Alpha actinin. Anti-Alpha actinin Antibody (8E638) can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $529 | 7-10 days |
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Concentration:1.0 mg/mL
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Antigen Details
Chemical Properties
| Description | Anti-Alpha actinin Antibody (8E638) is a Mouse antibody targeting Alpha actinin. Anti-Alpha actinin Antibody (8E638) can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P. |
| Synonyms | Non-Muscle alpha-Actinin-1, FLJ54432, FLJ40884, F-Actin Cross-Linking Protein, BDPLT15, alpha-actinin-1, alpha-actinin cytoskeletal isoform, alpha Actinin 1, ACTN1, ACTN 1, Actinin, alpha 1, Actinin alpha 1, Actinin 1 Smooth Muscle |
| Ig Type | IgG |
| Clone | 8E638 |
| Reactivity | (predicted:Human,Mouse,Rat) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:500-1000; ICC/IF: 1:100-500; IF: 1:500-1000; ELISA: 1:5000-10000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cytoplasm > cytoskeleton. Cytoplasm > myofibril > sarcomere > Z line. Cell membrane. Cell junction. Cell projection › ruffle. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant Protein: human Alpha-actinin-1 protein 1-205/894 (C-6x His-Tag) |
| Antigen Species | Human |
| Gene Name | ACTN1 |
| Gene ID | |
| Protein Name | alpha-actinin-1 |
| Uniprot ID | |
| Biology Area | Mesoderm,Actin Binding Proteins,Actin Crosslinking,Mesoderm |
| Function | F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. |
| Molecular Weight | Theoretical: 103 kDa. |
| Color | Transparent |
| Appearance | Liquid |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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