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Anti-Alpha actinin Antibody (8E638) (Synonyms: Non-Muscle alpha-Actinin-1, FLJ54432, FLJ40884, F-Actin Cross-...)

Catalog No. TMAB-00103 Copy Product Info
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Anti-Alpha actinin Antibody (8E638) is a Mouse antibody targeting Alpha actinin. Anti-Alpha actinin Antibody (8E638) can be used in ELISA, ICC/IF, IF, IHC-Fr, IHC-P.

Anti-Alpha actinin Antibody (8E638)

Copy Product Info
🥰Excellent
Catalog No. TMAB-00103
Synonyms Non-Muscle alpha-Actinin-1, FLJ54432, FLJ40884, F-Actin Cross-Linking Protein, BDPLT15, alpha-actinin-1, alpha-actinin cytoskeletal isoform, alpha Actinin 1, ACTN1, ACTN 1, Actinin, alpha 1, Actinin alpha 1, Actinin 1 Smooth Muscle

Anti-Alpha actinin Antibody (8E638) is a Mouse antibody targeting Alpha actinin. Anti-Alpha actinin Antibody (8E638) can be used in ELISA, ICC/IF, IF, IHC-Fr, IHC-P.

Anti-Alpha actinin Antibody
(8E638)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Liquid
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Product Introduction

Bioactivity
Description
Anti-Alpha actinin Antibody (8E638) is a Mouse antibody targeting Alpha actinin. Anti-Alpha actinin Antibody (8E638) can be used in ELISA, ICC/IF, IF, IHC-Fr, IHC-P.
SynonymsNon-Muscle alpha-Actinin-1, FLJ54432, FLJ40884, F-Actin Cross-Linking Protein, BDPLT15, alpha-actinin-1, alpha-actinin cytoskeletal isoform, alpha Actinin 1, ACTN1, ACTN 1, Actinin, alpha 1, Actinin alpha 1, Actinin 1 Smooth Muscle
Ig Type
IgG
Clone
8E638
Reactivity
(predicted:Human,Mouse,Rat)
Application
Recommended Dose
ELISA=1:5000-10000; ICC/IF=1:100-500; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationCytoplasm > cytoskeleton. Cytoplasm > myofibril > sarcomere > Z line. Cell membrane. Cell junction. Cell projection › ruffle.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
Recombinant Protein: human Alpha-actinin-1 protein 1-205/894 (C-6x His-Tag)
Antigen Species
Human
Gene Name
ACTN1
Gene ID
Protein Name
alpha-actinin-1
Uniprot ID
Biology Area
Mesoderm,Actin Binding Proteins,Actin Crosslinking,Mesoderm
Function
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Chemical Properties
Molecular WeightTheoretical: 103 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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