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Anti-Alpha actinin Antibody (8E638)

😃Good
Catalog No. TMAB-00103

Anti-Alpha actinin Antibody (8E638) is a Mouse antibody targeting Alpha actinin. Anti-Alpha actinin Antibody (8E638) can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA.

Anti-Alpha actinin Antibody (8E638)

Anti-Alpha actinin Antibody (8E638)

😃Good
Catalog No. TMAB-00103
Anti-Alpha actinin Antibody (8E638) is a Mouse antibody targeting Alpha actinin. Anti-Alpha actinin Antibody (8E638) can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$221 7-10 days
100 μL$372 7-10 days
200 μL$529 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Alpha actinin Antibody (8E638) is a Mouse antibody targeting Alpha actinin. Anti-Alpha actinin Antibody (8E638) can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
Ig Type
IgG
Clone
8E638
Reactivity
(predicted:Human,Mouse,Rat)
Application
IHC-P,IHC-Fr,ICC/IF,IF,ELISA
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:500-1000; ICC/IF: 1:100-500; IF: 1:500-1000; ELISA: 1:5000-10000
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationCytoplasm > cytoskeleton. Cytoplasm > myofibril > sarcomere > Z line. Cell membrane. Cell junction. Cell projection › ruffle.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
Recombinant Protein: human Alpha-actinin-1 protein 1-205/894 (C-6x His-Tag)
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Mesoderm,Actin Binding Proteins,Actin Crosslinking,Mesoderm
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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