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Anti-Alpha actinin Antibody (8E638) is a Mouse antibody targeting Alpha actinin. Anti-Alpha actinin Antibody (8E638) can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $221 | 7-10 days | |
100 μL | $372 | 7-10 days | |
200 μL | $529 | 7-10 days |
Description | Anti-Alpha actinin Antibody (8E638) is a Mouse antibody targeting Alpha actinin. Anti-Alpha actinin Antibody (8E638) can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA. |
Ig Type | IgG |
Clone | 8E638 |
Reactivity | (predicted:Human,Mouse,Rat) |
Application | IHC-P,IHC-Fr,ICC/IF,IF,ELISA |
Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:500-1000; ICC/IF: 1:100-500; IF: 1:500-1000; ELISA: 1:5000-10000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Subcellular Localization | Cytoplasm > cytoskeleton. Cytoplasm > myofibril > sarcomere > Z line. Cell membrane. Cell junction. Cell projection › ruffle. |
Construction | Hybridoma Monoclonal Antibody |
Purification | Protein G purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Immunogen | Recombinant Protein: human Alpha-actinin-1 protein 1-205/894 (C-6x His-Tag) |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | Mesoderm,Actin Binding Proteins,Actin Crosslinking,Mesoderm |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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