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Anti-Phospho-GAB2 (Tyr452) Polyclonal Antibody
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Catalog No. TMAC-01586
Alias p-GAB2 (Y452), p-GAB2 (Tyr452), GAB2 (p-Y452), GAB2 (p-Tyr452)
Anti-Phospho-GAB2 (Tyr452) Polyclonal Antibody is a Rabbit antibody targeting Phospho-GAB2 (Tyr452). Anti-Phospho-GAB2 (Tyr452) Polyclonal Antibody can be used in WB.
Anti-Phospho-GAB2 (Tyr452) Polyclonal Antibody
Anti-Phospho-GAB2 (Tyr452) Polyclonal Antibody
😃Good
Catalog No. TMAC-01586Alias p-GAB2 (Y452), p-GAB2 (Tyr452), GAB2 (p-Y452), GAB2 (p-Tyr452)
Anti-Phospho-GAB2 (Tyr452) Polyclonal Antibody is a Rabbit antibody targeting Phospho-GAB2 (Tyr452). Anti-Phospho-GAB2 (Tyr452) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $216 | 7-10 days | |
| 100 μL | $317 | 7-10 days |
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| Description | Anti-Phospho-GAB2 (Tyr452) Polyclonal Antibody is a Rabbit antibody targeting Phospho-GAB2 (Tyr452). Anti-Phospho-GAB2 (Tyr452) Polyclonal Antibody can be used in WB. |
| Synonyms | p-GAB2 (Y452), p-GAB2 (Tyr452), GAB2 (p-Y452), GAB2 (p-Tyr452) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of extracts from JK, using Gab2 (Phospho-Tyr452) antibody TMAC-01586. The lane on the right is treated with the synthesized peptide. |
| Application | |
| Recommended Dose | WB: 1:500-3000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 452 (D-N-Y(p)-V-P) derived from Human Gab2 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 75 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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