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PLXNA1 Protein, Human, Recombinant (His)

Catalog No. TMPK-01232
Synonyms: Plexin A1, Semaphorin receptor NOV, NOV, PLXN1

PLXNA1 (Plexin A1) is a member of plexin family that are the receptors of semaphorins. It is involved in cell migration and neuronal repulsion by affecting cytoskeletal remodeling. PLXNA1 can bind class 6 semaphorins and bind the class 3 semaphorins indirectly via Neuropilin-1 and -2.

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PLXNA1 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 418.00
500 μg 5 days $ 1,670.00
1 mg 5 days $ 2,800.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description PLXNA1 (Plexin A1) is a member of plexin family that are the receptors of semaphorins. It is involved in cell migration and neuronal repulsion by affecting cytoskeletal remodeling. PLXNA1 can bind class 6 semaphorins and bind the class 3 semaphorins indirectly via Neuropilin-1 and -2.
Species Human
Expression System HEK293
Tag C-His
Accession Number Q9UIW2
Synonyms Plexin A1, Semaphorin receptor NOV, NOV, PLXN1
Construction Recombinant Human PLXNA1 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Glu27-Pro1244.[Accession |Q9UIW2]
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight The protein has a predicted MW of 135 kDa. Due to glycosylation, the protein migrates to 140-155 kDa based on Tris-Bis PAGE result.
Endotoxin Less than 1EU per μg by the LAL method.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability & Storage

-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background PLXNA1 (Plexin A1) is a member of plexin family that are the receptors of semaphorins. It is involved in cell migration and neuronal repulsion by affecting cytoskeletal remodeling. PLXNA1 can bind class 6 semaphorins and bind the class 3 semaphorins indirectly via Neuropilin-1 and -2.

References and Literature

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Keywords

PLXNA1 Protein, Human, Recombinant (His) Plexin A1, Semaphorin receptor NOV, NOV, PLXN1 recombinant recombinant-proteins proteins protein

 

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