Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, His)

Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-50 KDa and the accession number is L0N6D9.

Pack Size	Availability	Price/USD
10 μg	5 days	$ 86.00
50 μg	5 days	$ 262.00
500 μg	5 days	$ 2,150.00
1 mg	5 days	$ 3,220.00

Pack Size

Availability

Price/USD

Quantity

10 μg

5 days

$ 86.00

50 μg

5 days

$ 262.00

500 μg

5 days

$ 2,150.00

1 mg

5 days

$ 3,220.00

Description

Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-50 KDa and the accession number is L0N6D9.

Species	Cynomolgus
Expression System	Human Cells
Tag	C-6His
Accession Number	L0N6D9
Synonyms	LNIR, Ig superfamily receptor LNIR, PRR4, Poliovirus receptor-related protein 4, PVRL4, Nectin-4
Amino Acid	Gly32-Ser349
Construction	Recombinant Cynomolgus Poliovirus Receptor-Related Protein 4 is produced by our Mammalian expression system and the target gene encoding Gly32-Ser349 is expressed with a 6His tag at the C-terminus.
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight	38-50 KDa, reducing conditions

Endotoxin	Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Stability & Storage	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background	Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.

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Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, His)

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