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Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, His)
(Synonyms: PVRL4, PRR4, Poliovirus receptor-related protein 4, Nectin-4, LNIR, Ig superfamily receptor LNIR) Copy Product InfoSynonyms: PVRL4, PRR4, Poliovirus receptor-related protein 4, Nectin-4, LNIR, Ig superfamily receptor LNIR
Catalog No. TMPJ-00309 Copy Product Info
Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-50 KDa and the accession number is L0N6D9.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $55 | 4-6 weeks | 4-6 weeks | |
| 10 µg | $86 | 4-6 weeks | 4-6 weeks | |
| 20 µg | $137 | 4-6 weeks | 4-6 weeks | |
| 50 µg | $262 | 4-6 weeks | 4-6 weeks | |
| 100 µg | $488 | 4-6 weeks | 4-6 weeks | |
| 200 µg | $923 | 4-6 weeks | 4-6 weeks | |
| 500 µg | $2,150 | 4-6 weeks | 4-6 weeks | |
| 1 mg | $3,220 | 4-6 weeks | 4-6 weeks |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | 1. Loaded Anti-Human Nectin-4 mAb-mFc on AMQ Biosensor, can bind Cynomolgus Nectin-4-His with an affinity constant of 1.57 nM as determined in BLI assay. (Regularly tested)
2. Immobilized Anti-Human Nectin-4 mAb-mFc at 2μg/ml (100 μl/well) can bind Cynomolgus Nectin-4-His. The ED50 of Cynomolgus Nectin-4 -His is 36.5 ng/ml. (Regularly tested) |
| Description | Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-50 KDa and the accession number is L0N6D9. |
| Species | Cynomolgus |
| Expression System | HEK293 Cells |
| Tag | C-6xHis |
| Accession Number | L0N6D9 |
| Amino Acid | Gly32-Ser349 |
| Construction | Gly32-Ser349 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | PVRL4, PRR4, Poliovirus receptor-related protein 4, Nectin-4, LNIR, Ig superfamily receptor LNIR |
| Research Background | Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. |
| Molecular Weight | 38-50 KDa (reducing condition) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, His) chemical structure | Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, His) molecular weight
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