SMAD5 Protein, Mouse, Recombinant

Name: SMAD5 Protein, Mouse, Recombinant
Brand: TargetMol
SKU: TMPY-03469
Rating: 4.5 (1 reviews)

(Synonyms: SMAD family member 5, MusMLP, Madh5, Dwf-C, AI451355, 1110051M15Rik) Copy Product Info

Synonyms: SMAD family member 5, MusMLP, Madh5, Dwf-C, AI451355, 1110051M15Rik

Catalog No. TMPY-03469 Copy Product Info

SMAD5 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 52.2 kDa and the accession number is P97454.

Pack Size	Price	USA Stock	Global Stock
5 µg	$68	7-10 days	7-10 days
10 µg	$112	7-10 days	7-10 days
20 µg	$188	7-10 days	7-10 days
50 µg	$370	7-10 days	7-10 days
100 µg	$716	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	SMAD5 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 52.2 kDa and the accession number is P97454.
Species	Mouse
Expression System	Baculovirus Insect Cells
Tag	Tag Free
Accession Number	P97454
Construction	A DNA sequence encoding the mouse SMAD5 (P97454) (Thr2-Ser465) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus. Predicted N terminal: Gly
Protein Purity	> 90 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 500 mM Nacl, 10% glycerol, pH8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	SMAD family member 5, MusMLP, Madh5, Dwf-C, AI451355, 1110051M15Rik
Research Background	SMAD5 is a member of the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD5 is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. It is also involved in cell signalling and modulates signals of bone morphogenetic proteins (BMP's). The binding of ligands causes the oligomerization and phosphorylation of the SMAD5 protein. SMAD5 is a receptor regulated SMAD (R-SMAD) and is activated by bone morphogenetic protein type 1 receptor kinase.

Chemical Properties

Molecular Weight

52.2 kDa (predicted); 57 kDa (reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.