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Anti-CD166/ALCAM Antibody-APC (3O275)
🥰Excellent
Catalog No. TMAY-00159A
Anti-CD166/ALCAM Antibody-APC (3O275) is a APC-conjugated Mouse antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody-APC (3O275) can be used in FCM.
Anti-CD166/ALCAM Antibody-APC (3O275)
Anti-CD166/ALCAM Antibody-APC (3O275)
🥰Excellent
Catalog No. TMAY-00159A
Anti-CD166/ALCAM Antibody-APC (3O275) is a APC-conjugated Mouse antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody-APC (3O275) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD166/ALCAM Antibody-APC (3O275) is a APC-conjugated Mouse antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody-APC (3O275) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 3O275 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CD166/ALCAM expression on Jurkat cells. Cells were stained with APC-conjugated anti-Human CD166/ALCAM. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD166 / ALCAM (rh CD166 / ALCAM; TMPY-01578; NP_001618.2; Met 1-Ala 526) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-CD6) and homophilic (ALCAM-ALCAM) cell-cell interactions. ALCAM/CD6 interaction plays a role in T cell development and T cell regulation, as well as in the binding of T- and B-cells to activated leukocytes. Recently, homophilic (ALCAM-ALCAM) adhesion was shown to play important roles in tight cell-to-cell interaction and regulation of stem cell differentiation. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells involved in dynamic growth and/or migration, including neural development, branching organ development, hematopoiesis, immune response and tumor progression. And CD166 is regarded as a potential novel breast cancer indicator and therapeutic target. |
| Conjucates | APC |
| Others Formats | Unconjugated/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human CD166 / ALCAM protein (TMPY-01578) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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