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Anti-Serpin B6 Antibody (6G141)

😃Good
Catalog No. TMAY-02421
Alias SPI3, serpin peptidase inhibitor, clade B (ovalbumin), member 6, Serpin B6, RP1-90J20.6, PTI, PI-6, PI6, MSTP057, MGC111370, DKFZp686I04222, DFNB91, CAP

Anti-Serpin B6 Antibody (6G141) is a Rabbit antibody targeting Serpin B6. Anti-Serpin B6 Antibody (6G141) can be used in ELISA.

Anti-Serpin B6 Antibody (6G141)

Anti-Serpin B6 Antibody (6G141)

😃Good
Catalog No. TMAY-02421Alias SPI3, serpin peptidase inhibitor, clade B (ovalbumin), member 6, Serpin B6, RP1-90J20.6, PTI, PI-6, PI6, MSTP057, MGC111370, DKFZp686I04222, DFNB91, CAP
Anti-Serpin B6 Antibody (6G141) is a Rabbit antibody targeting Serpin B6. Anti-Serpin B6 Antibody (6G141) can be used in ELISA.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Serpin B6 Antibody (6G141) is a Rabbit antibody targeting Serpin B6. Anti-Serpin B6 Antibody (6G141) can be used in ELISA.
AliasSPI3, serpin peptidase inhibitor, clade B (ovalbumin), member 6, Serpin B6, RP1-90J20.6, PTI, PI-6, PI6, MSTP057, MGC111370, DKFZp686I04222, DFNB91, CAP
Ig Type
Monoclonal Rabbit IgG
Clone
6G141
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human SerpinB6 (rh SerpinB6; TMPY-02242; AAB30320.1; Asp 2-Pro 376).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundSerpinB6, also known as Cytoplasmic antiproteinase, Peptidase inhibitor 6, Placental thrombin inhibitor, SERPINB6 and PI-6, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. SerpinB6 / PI-6 is an inhibitor of cathepsin G, kallikrein-8 and thrombin. It may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss. SerpinB6 / PI-6 is expressed in keratinocytes (at protein level). It is also found in placenta, cardiac muscle, lung, liver, kidney and pancreas. SerpinB6 / PI-6 is expressed in the inner ear hair cells. It’s expressed abundantly by normal mast cells in different tissues and by mast cells in mastocytoma lesions. SerpinB6 / PI-6 may be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. Defects in SerpinB6 are the cause of deafness autosomal recessive type 91 which is a form of non-syndromic deafness characterized by progressive and age-dependent sensorineural hearing loss. Vestibular function is normal.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human SerpinB6 protein (TMPY-02242)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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