Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-Osteoprotegerin Antibody (7E614)

😃Good
Catalog No. TMAY-00543
Alias tumor necrosis factor receptor superfamily member 11b, TR1, PDB5, OPG, OCIF, MGC29565

Anti-Osteoprotegerin Antibody (7E614) is a Rabbit antibody targeting Osteoprotegerin. Anti-Osteoprotegerin Antibody (7E614) can be used in ELISA.

Anti-Osteoprotegerin Antibody (7E614)

Anti-Osteoprotegerin Antibody (7E614)

😃Good
Catalog No. TMAY-00543Alias tumor necrosis factor receptor superfamily member 11b, TR1, PDB5, OPG, OCIF, MGC29565
Anti-Osteoprotegerin Antibody (7E614) is a Rabbit antibody targeting Osteoprotegerin. Anti-Osteoprotegerin Antibody (7E614) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
100 μL$269 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-Osteoprotegerin Antibody (7E614) is a Rabbit antibody targeting Osteoprotegerin. Anti-Osteoprotegerin Antibody (7E614) can be used in ELISA.
Aliastumor necrosis factor receptor superfamily member 11b, TR1, PDB5, OPG, OCIF, MGC29565
Ig Type
Monoclonal Rabbit IgG
Clone
7E614
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human Osteoprotegerin / TNFRSF11B (rh Osteoprotegerin / TNFRSF11B; TMPY-01724; NP_002537.3; Met 1-Leu 401).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundOsteoprotegerin or TNFRSF11B is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. Osteoprotegerin/TNFRSF11B acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. This protein may inhibit the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. Osteoprotegerin/TNFRSF11B also play a role in preventing arterial calcification, act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human Osteoprotegerin / TNFRSF11B protein (TMPY-01724)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Anti-Osteoprotegerin Antibody (7E614) | purchase Anti-Osteoprotegerin Antibody (7E614) | Anti-Osteoprotegerin Antibody (7E614) cost | order Anti-Osteoprotegerin Antibody (7E614)