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Anti-Phospho-MAPT (Ser214) Antibody (1K160)
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Catalog No. TMAH-00922
Alias TAU and MAPT, p-MAPT (Ser214), p-MAPT (S214), Phospho-MAPT (S214), Paired helical filament-tau, Neurofibrillary tangle protein, MTBT1, Microtubule-associated protein tau, MAPTL, MAPT (p-Ser214), MAPT (p-S214)
Anti-Phospho-MAPT (Ser214) Antibody (1K160) is an antibody targeting Phospho-MAPT (Ser214). Anti-Phospho-MAPT (Ser214) Antibody (1K160) can be used in ELISA, IHC.
Anti-Phospho-MAPT (Ser214) Antibody (1K160)
Anti-Phospho-MAPT (Ser214) Antibody (1K160)
😃Good
Catalog No. TMAH-00922Alias TAU and MAPT, p-MAPT (Ser214), p-MAPT (S214), Phospho-MAPT (S214), Paired helical filament-tau, Neurofibrillary tangle protein, MTBT1, Microtubule-associated protein tau, MAPTL, MAPT (p-Ser214), MAPT (p-S214)
Anti-Phospho-MAPT (Ser214) Antibody (1K160) is an antibody targeting Phospho-MAPT (Ser214). Anti-Phospho-MAPT (Ser214) Antibody (1K160) can be used in ELISA, IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $208 | 7-10 days | |
| 100 μL | $349 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Rabbit Monoclonal Application: ELISA, IHC Reactivity: Human |
| Alias | TAU and MAPT, p-MAPT (Ser214), p-MAPT (S214), Phospho-MAPT (S214), Paired helical filament-tau, Neurofibrillary tangle protein, MTBT1, Microtubule-associated protein tau, MAPTL, MAPT (p-Ser214), MAPT (p-S214) |
| Ig Type | Rabbit IgG |
| Clone | 1K160 |
| Reactivity | Human |
| Verified Activity | IHC image of TMAH-00922 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.12% DAB. |
| Application | ELISA, IHC |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Secreted. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human MAPT |
| Antigen Species | Human |
| Gene ID | 4137 |
| Uniprot ID | |
| Biology Area | Neuroscience, Signal transduction |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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