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trans-10-Heptadecenoic acid

Name: trans-10-Heptadecenoic acid
Brand: TargetMol
SKU: T78467
Price: 93 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T78467 Copy Product Info

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trans-10-Heptadecenoic acid is a trans-unsaturated fatty acid used as a molecular probe to study beta-oxidation mechanisms. It is metabolized via reductase-dependent and multifunctional enzyme-dependent pathways, participating in PHA synthesis and modulating intracellular carbon flux.

trans-10-Heptadecenoic acid

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Catalog No. T78467

Cas No. 126761-43-1

Pack Size	Price	USA Stock	Global Stock	Quantity
1 mg	$93	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Appearance:Liquid

Color:Transparent

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COA

Product Introduction

Bioactivity

Description

In vitro

In experiments using recombinant Saccharomyces cerevisiae expressing the peroxisomal PHA synthase, trans-10-Heptadecenoic acid was used to evaluate the β-oxidation process of trans-unsaturated fatty acids. The results showed that this compound is converted into polyhydroxyalkanoate under the action of 2,4-dienoyl-CoA reductase and Delta3, Δ2-enoyl-CoA isomerase; however, in the absence of these reductases, trans-10-heptadecenoic acid is degraded via the enoyl-CoA hydrolase II of the multifunctional enzyme (MFE). Studies have confirmed that this metabolic process leads to substantial intracellular carbon efflux via both reductase-dependent and direct MFE-dependent pathways [1].

Chemical Properties

Molecular Weight	268.43
Formula	C₁₇H₃₂O₂
Cas No.	126761-43-1
Smiles	C(CCC/C=C/CCCCCC)CCCCC(O)=O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (111.76 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7254 mL	18.6268 mL	37.2537 mL	186.2683 mL
5 mM	0.7451 mL	3.7254 mL	7.4507 mL	37.2537 mL
10 mM	0.3725 mL	1.8627 mL	3.7254 mL	18.6268 mL
20 mM	0.1863 mL	0.9313 mL	1.8627 mL	9.3134 mL
50 mM	0.0745 mL	0.3725 mL	0.7451 mL	3.7254 mL
100 mM	0.0373 mL	0.1863 mL	0.3725 mL	1.8627 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc