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2-Methylthioadenosine diphosphate trisodium
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Catalog No. T23581Cas No. 475193-31-8
Alias 2-Methylthio-ADP trisodium, 2-MeS-ADP trisodium, 2MeSADP trisodium, 2 Methylthio ADP trisodium, 2 MeS ADP trisodium
2-Methylthioadenosine diphosphate trisodium (2-MeS-ADP) is the salt form of 2-Methylthioadenosine diphosphate, a synthetic analog of adenosine diphosphate (ADP), a potent purinergic P2Y receptor agonist that agonizes human P2Y13 at nanomolar levels, mouse P2Y13 and human P2Y12, induces platelet aggregation and morphological changes, and is indicated for neurological and cardiovascular disease studies.
2-Methylthioadenosine diphosphate trisodium
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Catalog No. T23581Alias 2-Methylthio-ADP trisodium, 2-MeS-ADP trisodium, 2MeSADP trisodium, 2 Methylthio ADP trisodium, 2 MeS ADP trisodiumCas No. 475193-31-8
2-Methylthioadenosine diphosphate trisodium (2-MeS-ADP) is the salt form of 2-Methylthioadenosine diphosphate, a synthetic analog of adenosine diphosphate (ADP), a potent purinergic P2Y receptor agonist that agonizes human P2Y13 at nanomolar levels, mouse P2Y13 and human P2Y12, induces platelet aggregation and morphological changes, and is indicated for neurological and cardiovascular disease studies.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $143 | 35 days | 35 days | |
| 5 mg | $633 | 35 days | 35 days | |
| 10 mg | $973 | 35 days | 35 days |
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| Description | 2-Methylthioadenosine diphosphate trisodium (2-MeS-ADP) is the salt form of 2-Methylthioadenosine diphosphate, a synthetic analog of adenosine diphosphate (ADP), a potent purinergic P2Y receptor agonist that agonizes human P2Y13 at nanomolar levels, mouse P2Y13 and human P2Y12, induces platelet aggregation and morphological changes, and is indicated for neurological and cardiovascular disease studies. |
| In vitro | 2-Methylthioadenosine diphosphate trisodium is a potent inhibitor of cyclic AMP accumulation in intact platelets exposed to PGE1 and is a potent human platelet aggregator.[1] |
| Synonyms | 2-Methylthio-ADP trisodium, 2-MeS-ADP trisodium, 2MeSADP trisodium, 2 Methylthio ADP trisodium, 2 MeS ADP trisodium |
| Molecular Weight | 539.24 |
| Formula | C11H14N5Na3O10P2S |
| Cas No. | 475193-31-8 |
| Smiles | O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP([O-])([O-])=O)([O-])=O)N2C3=NC(SC)=NC(N)=C3N=C2.[Na+].[Na+].[Na+] |
| Relative Density. | no data available |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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