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2'-MeCCPA

Name: 2'-MeCCPA
Brand: TargetMol
SKU: T22489
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T22489Cas No. 205171-12-6

Alias 2-Chloro-N-cyclopentyl-2′-C-methyladenosine

2'-MeCCPA is a potent and highly selective A1 adenosine receptor (A1AR) agonist with a K-value of 1.8 nM for AR. 2'-MeCCPA inhibits trichostatin-stimulated adenylate cyclase activity with an IC value of 13.1 nM, exhibits analgesic activity, and can be used in the study of HCV.

2'-MeCCPA

🥰Excellent

Purity: 99.93%

Catalog No. T22489Alias 2-Chloro-N-cyclopentyl-2′-C-methyladenosineCas No. 205171-12-6

Pack Size	Price	Availability
1 mg	$30	In Stock
5 mg	$65	In Stock
10 mg	$125	In Stock
25 mg	$208	In Stock
50 mg	$317	In Stock
100 mg	$457	In Stock
200 mg	$648	In Stock

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Purity:99.93%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	2'-MeCCPA is a potent and highly selective A1 adenosine receptor (A1AR) agonist with a K-value of 1.8 nM for AR. 2'-MeCCPA inhibits trichostatin-stimulated adenylate cyclase activity with an IC value of 13.1 nM, exhibits analgesic activity, and can be used in the study of HCV.
In vivo	During reperfusion, 2'-MeCCPA (1 nM-1 M) significantly reduces the infarct area and risk ratio in male Sprague-Dawley rats[2].
Synonyms	2-Chloro-N-cyclopentyl-2′-C-methyladenosine

Chemical Properties

Molecular Weight	383.83
Formula	C₁₆H₂₂ClN₅O₄
Cas No.	205171-12-6
Smiles	C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(NC3CCCC3)nc(Cl)nc12
Relative Density.	1.76g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (260.53 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6053 mL	13.0266 mL	26.0532 mL	130.2660 mL
5 mM	0.5211 mL	2.6053 mL	5.2106 mL	26.0532 mL
10 mM	0.2605 mL	1.3027 mL	2.6053 mL	13.0266 mL
20 mM	0.1303 mL	0.6513 mL	1.3027 mL	6.5133 mL
50 mM	0.0521 mL	0.2605 mL	0.5211 mL	2.6053 mL
100 mM	0.0261 mL	0.1303 mL	0.2605 mL	1.3027 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc