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2'-MeCCPA (Synonyms: 2-Chloro-N-cyclopentyl-2′-C-methyladenosine)

Name: 2'-MeCCPA
Brand: TargetMol
SKU: T22489
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T22489 Copy Product Info

Purity: 99.96%

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2'-MeCCPA is a potent and highly selective A1 adenosine receptor (A1AR) agonist with a K-value of 1.8 nM for AR. 2'-MeCCPA inhibits trichostatin-stimulated adenylate cyclase activity with an IC value of 13.1 nM, exhibits analgesic activity, and can be used in the study of HCV.

2'-MeCCPA

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Catalog No. T22489

Synonyms 2-Chloro-N-cyclopentyl-2′-C-methyladenosine

Cas No. 205171-12-6

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Pack Size	Price	USA Stock	Global Stock
1 mg	$30	In Stock	In Stock
5 mg	$65	In Stock	In Stock
10 mg	$125	In Stock	In Stock
25 mg	$208	In Stock	In Stock
50 mg	$317	In Stock	In Stock
100 mg	$457	-	In Stock
200 mg	$648	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.96%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	2'-MeCCPA is a potent and highly selective A1 adenosine receptor (A1AR) agonist with a K-value of 1.8 nM for AR. 2'-MeCCPA inhibits trichostatin-stimulated adenylate cyclase activity with an IC value of 13.1 nM, exhibits analgesic activity, and can be used in the study of HCV.
In vivo	During reperfusion, 2'-MeCCPA (1 nM-1 M) significantly reduces the infarct area and risk ratio in male Sprague-Dawley rats[2].
Synonyms	2-Chloro-N-cyclopentyl-2′-C-methyladenosine

Chemical Properties

Molecular Weight	383.83
Formula	C₁₆H₂₂ClN₅O₄
Cas No.	205171-12-6
Smiles	C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(NC3CCCC3)nc(Cl)nc12
Relative Density.	1.76g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (260.53 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6053 mL	13.0266 mL	26.0532 mL	130.2660 mL
5 mM	0.5211 mL	2.6053 mL	5.2106 mL	26.0532 mL
10 mM	0.2605 mL	1.3027 mL	2.6053 mL	13.0266 mL
20 mM	0.1303 mL	0.6513 mL	1.3027 mL	6.5133 mL
50 mM	0.0521 mL	0.2605 mL	0.5211 mL	2.6053 mL
100 mM	0.0261 mL	0.1303 mL	0.2605 mL	1.3027 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc