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TSLP Protein, Mouse, Recombinant (His)

(Synonyms: TSLP, thymic stromal lymphopoietin) Copy Product Info

Synonyms: TSLP, thymic stromal lymphopoietin

Catalog No. TMPY-02428 Copy Product Info
Purity: 97.1%
TSLP Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.4 kDa and the accession number is Q9JIE6.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$44-In Stock
10 µg$68-In Stock
20 µg$108-In Stock
50 µg$198-In Stock
100 µg$346-In Stock
200 µg$5857-10 days7-10 days
500 µg$1,1607-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:97.1%
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
TSLP Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.4 kDa and the accession number is Q9JIE6.
Species
Mouse
Expression System
HEK293 Cells
TagC-His
Accession NumberQ9JIE6
ConstructionA DNA sequence encoding the mouse TSLP (Q9JIE6) (Met 1-Glu 140) was expressed, with a C-terminal polyhistidine tag. Predicted N terminal: Tyr 20
Protein Purity
> 90 % as determined by SDS-PAGE
TSLP Protein, Mouse, Recombinant (His)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionReconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
SynonymsTSLP, thymic stromal lymphopoietin
Research Background
Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is a cytokine expressed by epithelial cells, including keratinocytes, and is important in allergic inflammation. Subsequent studies have shown that TSLP promotes T helper type 2 (TH2) cell responses associated with immunity to some helminth parasites and the pathogenesis of many inflammatory diseases, including atopic dermatitis and asthma. TSLP can promote TH2 cytokine-associated inflammation by directly promoting the effector functions of CD4+TH2 cells, basophils and other granulocyte populations while simultaneously limiting the expression of DC-derived proinflammatory cytokines and promoting regulatory T cell responses in peripheral tissues.
Chemical Properties
Molecular Weight15.4 kDa (predicted); 22-27 kDa (reducing condition, due to glycosylation)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: TSLP Protein, Mouse, Recombinant (His) chemical structure | TSLP Protein, Mouse, Recombinant (His) molecular weight