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Cephalothin sodium

Name: Cephalothin sodium
Brand: TargetMol
SKU: T1122
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1122Cas No. 58-71-9

Alias Cephalothin sodium salt, Cefalotin sodium

Cephalothin sodium (Cefalotin) binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cephalothin sodium (Cefalotin) is the sodium salt form of cephalothin, a semisynthetic, beta-lactam, the first-generation cephalosporin antibiotic with bactericidal activity. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Cephalothin sodium

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Purity: 99.17%

Catalog No. T1122Alias Cephalothin sodium salt, Cefalotin sodiumCas No. 58-71-9

Pack Size	Price	USA Warehouse	Global Warehouse
200 mg	$34	-	In Stock
500 mg	$53	-	In Stock
1 g	$77	-	In Stock
2 g	$112	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.17%

Color:White to Yellow

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description

Synonyms

Cephalothin sodium salt, Cefalotin sodium

Chemical Properties

Molecular Weight	418.4
Formula	C₁₆H₁₅N₂NaO₆S₂
Cas No.	58-71-9
Smiles	[Na+].CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc1cccs1)C2=O)C([O-])=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 119.5 mM, Sonication is recommended.

DMSO: 51 mg/mL (121.89 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.78 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3901 mL	11.9503 mL	23.9006 mL	119.5029 mL
5 mM	0.4780 mL	2.3901 mL	4.7801 mL	23.9006 mL
10 mM	0.2390 mL	1.1950 mL	2.3901 mL	11.9503 mL
20 mM	0.1195 mL	0.5975 mL	1.1950 mL	5.9751 mL
50 mM	0.0478 mL	0.2390 mL	0.4780 mL	2.3901 mL
100 mM	0.0239 mL	0.1195 mL	0.2390 mL	1.1950 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc