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Anti-TYROBP Polyclonal Antibody is a Rabbit antibody targeting TYROBP. Anti-TYROBP Polyclonal Antibody can be used in FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $220 | 7-10 days | |
100 μL | $372 | 7-10 days | |
200 μL | $528 | 7-10 days |
Description | Anti-TYROBP Polyclonal Antibody is a Rabbit antibody targeting TYROBP. Anti-TYROBP Polyclonal Antibody can be used in FCM. |
Alias | TYRO protein tyrosine kinase binding protein, TYOBP, PLOSL, Killer-activating receptor-associated protein, KAR-associated protein, KARAP, DNAX-activation protein 12, DAP12, DAP 12 |
Ig Type | IgG |
Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Sheep) |
Verified Activity | Blank control: mouse splenocytes (blue) Isotype Control Antibody: Rabbit IgG-Pe (orange); Primary Antibody Dilution: 1 μL in 100 μL 1X PBS containing 0.5% BSA (green). |
Application | FCM |
Recommended Dose | FCM: 1μg/Test |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Membrane. |
Construction | Hybridoma Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010] |
Immunogen | KLH conjugated synthetic peptide: human DAP12 |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | Transmembrane |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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