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Terlipressin Acetate

🥰Excellent

Catalog No. T13920LCas No. 1884420-36-3

Alias Terlipressin acetate anhydrous

Terlipressin Acetate, a highly selective vasopressin V1 receptor agonist, on oxygen and glucose deprivation/re-oxygenation (OGD/R)-induced damage in intestinal epithelial cells (IEC-6).Terlipressin acetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin acetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research.

Terlipressin Acetate

🥰Excellent

Purity: 99.69%

Catalog No. T13920LAlias Terlipressin acetate anhydrousCas No. 1884420-36-3

Pack Size	Price	Availability
5 mg	$41	In Stock
10 mg	$56	In Stock
25 mg	$105	In Stock
50 mg	$138	In Stock
100 mg	$218	In Stock
200 mg	$327	In Stock

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Purity:99.69%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Terlipressin Acetate, a highly selective vasopressin V1 receptor agonist, on oxygen and glucose deprivation/re-oxygenation (OGD/R)-induced damage in intestinal epithelial cells (IEC-6).Terlipressin acetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin acetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research.
In vitro	Incubation with 25 nM terlipressin significantly improved cell viability, proliferation and apoptosis. Furthermore, terlipressin inhibited the secretion of TNF-α and 15-F2t-isoprostane from IEC-6 cells following OGD/R[1].
In vivo	Using a mouse nonlethal hepatic IR model, we found terlipressin administration significantly ameliorated IR-induced liver apoptosis, necrosis and inflammation[2].
Synonyms	Terlipressin acetate anhydrous

Chemical Properties

Molecular Weight	1347.5
Formula	C₅₆H₈₂N₁₆O₁₉S₂
Cas No.	1884420-36-3
Smiles	CC(O)=O.CC(O)=O.[H][C@@]1(Cc2ccccc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)NCC(N)=O)NC(=O)CNC(=O)CNC(=O)CN
Relative Density.	no data available
Color	White
Appearance	Solid
Sequence	Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys4-Cys9)
Sequence Short	GGGCYFQNCPKG-NH2 (Disulfide bridge: Cys4-Cys9)

Storage & Solubility Information

Storage

keep away from moisture,store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 95 mg/mL (70.5 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.7421 mL	3.7106 mL	7.4212 mL	37.1058 mL
5 mM	0.1484 mL	0.7421 mL	1.4842 mL	7.4212 mL
10 mM	0.0742 mL	0.3711 mL	0.7421 mL	3.7106 mL
20 mM	0.0371 mL	0.1855 mL	0.3711 mL	1.8553 mL
50 mM	0.0148 mL	0.0742 mL	0.1484 mL	0.7421 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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