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(S,R,S)-AHPC-Boc
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Catalog No. T77916Cas No. 1448189-98-7
Alias VH032-Boc
(S,R,S)-AHPC-Boc (VH032-Boc) is a ligand for von Hippel-Lindau (VHL) protein recruitment in PROTAC technology [1].
(S,R,S)-AHPC-Boc
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Catalog No. T77916Alias VH032-BocCas No. 1448189-98-7
(S,R,S)-AHPC-Boc (VH032-Boc) is a ligand for von Hippel-Lindau (VHL) protein recruitment in PROTAC technology [1].
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
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| 5 mg | Inquiry | Backorder | Backorder | |
| 50 mg | Inquiry | Backorder | Backorder |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | (S,R,S)-AHPC-Boc (VH032-Boc) is a ligand for von Hippel-Lindau (VHL) protein recruitment in PROTAC technology [1]. |
| In vitro | The VHL protein serves as the substrate recognition component within both widely prevalent and essential Cullin RING E3 ubiquitin ligase complexes. It is a prominent E3 ligase utilized by bifunctional PROTACs to facilitate the ubiquitination and consequent proteasomal degradation of designated target proteins. |
| Synonyms | VH032-Boc |
| Molecular Weight | 530.68 |
| Formula | C27H38N4O5S |
| Cas No. | 1448189-98-7 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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