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Anti-Her2/ERBB2 Antibody-APC (6Z596)

🥰Excellent
Catalog No. TMAY-00042A

Anti-Her2/ERBB2 Antibody-APC (6Z596) is a APC-conjugated Rabbit antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody-APC (6Z596) can be used in FCM.

Anti-Her2/ERBB2 Antibody-APC (6Z596)

Anti-Her2/ERBB2 Antibody-APC (6Z596)

🥰Excellent
Catalog No. TMAY-00042A
Anti-Her2/ERBB2 Antibody-APC (6Z596) is a APC-conjugated Rabbit antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody-APC (6Z596) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-Her2/ERBB2 Antibody-APC (6Z596) is a APC-conjugated Rabbit antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody-APC (6Z596) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
Clone
6Z596
Reactivity
Human
Verified Activity
Analysis of anti-human ErbB2 on MCF-7 cells. MCF-7 cells were detached using 1X trypsin, washed, then stained with APC Rabbit anti-human ErbB2.
Application
FCM
Recommended Dose
5 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human ErbB2 / HER2 extracellular domain (rh ErbB2; TMPY-01137; NP_004439.2; Met 1-Thr 652) and conjugated with APC under optimum conditions, the unreacted APC was removed .
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundHuman epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
APC
Others Formats
Unconjugated/Biotin/FITC/PE
Antibody Types Available
5
Antigen Details
Immunogen
Recombinant Human ErbB2 protein (TMPY-01137)
Antigen Species
Human
Biology Area
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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