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Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody

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Catalog No. TMAC-00472

Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BRCA2 (Ser3291). Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody can be used in WB.

Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody

Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody

😃Good
Catalog No. TMAC-00472
Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BRCA2 (Ser3291). Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3187-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BRCA2 (Ser3291). Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundInvolved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint activation. Binds selectively to ssDNA, and to ssDNA in tailed duplexes and replication fork structures.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of Serine 3291 (F-V-S(p)-P-A) derived from Human BRCA2
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: >350 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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