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Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody
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Catalog No. TMAC-00472
Alias p-BRCA2 (Ser3291), p-BRCA2 (S3291), BRCA2 (p-Ser3291), BRCA2 (p-S3291)
Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BRCA2 (Ser3291). Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody can be used in WB.
Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody
Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody
😃Good
Catalog No. TMAC-00472Alias p-BRCA2 (Ser3291), p-BRCA2 (S3291), BRCA2 (p-Ser3291), BRCA2 (p-S3291)
Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BRCA2 (Ser3291). Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $216 | 7-10 days | |
| 100 μL | $318 | 7-10 days |
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Chemical Properties
| Description | Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BRCA2 (Ser3291). Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody can be used in WB. |
| Synonyms | p-BRCA2 (Ser3291), p-BRCA2 (S3291), BRCA2 (p-Ser3291), BRCA2 (p-S3291) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of extracts from 293 cells using BRCA2 (Phospho-Ser3291) Antibody TMAC-00472. The lane on the right is treated with the antigen-specific peptide. |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint activation. Binds selectively to ssDNA, and to ssDNA in tailed duplexes and replication fork structures. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of Serine 3291 (F-V-S(p)-P-A) derived from Human BRCA2 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: >350 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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