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Anti-Phospho-PLCg2 (Tyr759) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PLCg2 (Tyr759). Anti-Phospho-PLCg2 (Tyr759) Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $218 | 7-10 days | |
100 μL | $318 | 7-10 days |
Description | Anti-Phospho-PLCg2 (Tyr759) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PLCg2 (Tyr759). Anti-Phospho-PLCg2 (Tyr759) Polyclonal Antibody can be used in WB. |
Synonyms | p-PLCg2 (Y759), p-PLCg2 (Tyr759), PLCg2 (p-Y759), PLCg2 (p-Tyr759) |
Ig Type | IgG |
Reactivity | Human,Mouse |
Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200 (room temperature, 45min). 2. Western blot analysis of PLC gamma 2 (Phospho-Tyr759) expression in Hela (A), NIH3T3 (B), H9C2 (C) whole cell lysates. (Predicted band size: 147 kD; Observed band size: 147 kD). |
Application | |
Recommended Dose | WB: 1:1000-2000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
Appearance | Liquid |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Research Background | phospholipase C gamma 2(PLCG2) Homo sapiens The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014], |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | A synthesized phosphopeptide: human PLCγ2 around the phosphorylation site of Tyr759 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Actual: 148 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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